8GSV

Crystal structure of human BAK in complex with the Pxt1 BH3 domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
C	0042981	biological_process	regulation of apoptotic process
E	0042981	biological_process	regulation of apoptotic process
G	0042981	biological_process	regulation of apoptotic process
I	0042981	biological_process	regulation of apoptotic process
K	0042981	biological_process	regulation of apoptotic process
M	0042981	biological_process	regulation of apoptotic process
O	0042981	biological_process	regulation of apoptotic process
Q	0042981	biological_process	regulation of apoptotic process
S	0042981	biological_process	regulation of apoptotic process
U	0042981	biological_process	regulation of apoptotic process
W	0042981	biological_process	regulation of apoptotic process

Functional Information from PROSITE/UniProt

site_id	PS01080
Number of Residues	19
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFeSGi.NWGRVVALLgFGY

Chain	Residue	Details
A	LEU118-TYR136

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site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIaqrGGWVaAL

Chain	Residue	Details
A	TRP170-LEU181

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VgrqLAiIGDDINRR

Chain	Residue	Details
A	VAL74-ARG88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING:

Chain	Residue	Details
A	ASP160
A	HIS164
C	ASP160
C	HIS164
E	ASP160
E	HIS164
G	ASP160
G	HIS164
I	ASP160
I	HIS164
K	ASP160
K	HIS164
M	ASP160
M	HIS164
O	ASP160
O	HIS164
Q	ASP160
Q	HIS164
S	ASP160
S	HIS164
U	ASP160
U	HIS164
W	ASP160
W	HIS164

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