1MWU

Structure of methicillin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.60 A resolution.

Summary for 1MWU

• Entry DOI: 10.2210/pdb1mwu/pdb
• Related: 1MWR 1MWS 1MWT 1MWX
• Descriptor: penicillin-binding protein 2a, (2R,4S)-2-[(1R)-1-{[(2,6-dimethoxyphenyl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, ... (5 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam, d, d-transpeptidase, d-carboxypeptidase, methicillin, biosynthetic protein
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 2
• Total formula weight: 149023.23

Authors

Lim, D.C.,Strynadka, N.C.J. (deposition date: 2002-10-01, release date: 2002-11-06, Last modification date: 2012-02-15)

• Primary citation: Lim, D.,Strynadka, N.C.; Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.; Nat.Struct.Biol., 9:870-876, 2002; PubMed: 12389036

Experimental method

X-RAY DIFFRACTION (2.6 Å)