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1L7C
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alpha-catenin fragment, residues 385-651
分子名称: Alpha E-catenin
著者Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I.
登録日2002-03-14
公開日2002-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
J.Biol.Chem., 277, 2002
1H6G
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BU of 1h6g by Molmil
alpha-catenin M-domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ...
著者Yang, J, Dokurno, P, Tonks, N.K, Barford, D.
登録日2001-06-14
公開日2001-08-07
最終更新日2016-02-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
5H5M
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BU of 5h5m by Molmil
Crystal structure of HMP-1 M domain
分子名称: Alpha-catenin-like protein hmp-1
著者Kang, H, Bang, I, Weis, W.I, Choi, H.J.
登録日2016-11-08
公開日2017-03-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin
J. Biol. Chem., 292, 2017
6NR7
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Rerefinement of chicken vinculin
分子名称: (1R,2R,3S,4R,5R,6S)-4-{[(S)-[(2S)-2,3-dihydroxypropoxy](hydroxy)phosphoryl]oxy}-3,5,6-trihydroxycyclohexane-1,2-diyl bis[dihydrogen (phosphate)], PHOSPHATE ION, SULFATE ION, ...
著者Stec, B.
登録日2019-01-23
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Refined model of chicken vinculin suggests the mechanism of activation by helical super-bundle unfurling
To be published
6O3E
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mouse aE-catenin 82-883
分子名称: Catenin alpha-1
著者Pokutta, S, Weis, W.I.
登録日2019-02-26
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.001 Å)
主引用文献Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling.
Sci Rep, 9, 2019
6FQ4
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Structure of Chlamydial virulence factor TarP and vinculin head domain
分子名称: TarP-VBS1, Vinculin
著者Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T.
登録日2018-02-13
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.
FEBS Lett., 592, 2018
6FUY
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Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)
分子名称: CALCIUM ION, Vinculin
著者Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B.
登録日2018-02-28
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
3S90
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Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546)
分子名称: Talin-1, Vinculin
著者Yogesha, S.D, Sharff, A, Bricogne, G, Izard, T.
登録日2011-05-31
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20, 2011
6BFI
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Vinculin homolog in a sponge (phylum Porifera) reveals vertebrate-like cell adhesions involved in early multicellular evolution
分子名称: VIN1
著者Weis, W.I, Chodaparambil, J.V.
登録日2017-10-26
公開日2018-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution.
J. Biol. Chem., 293, 2018
5XA5
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Crystal structure of HMP-1-HMP-2 complex
分子名称: Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2
著者Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J.
登録日2017-03-11
公開日2017-08-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface.
J.Biol.Chem., 292, 2017
5XFL
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BU of 5xfl by Molmil
Crystal structure of the force-sensing device region of alpha N-catenin
分子名称: Catenin alpha-2
著者Hirano, Y, Hakoshima, T.
登録日2017-04-10
公開日2018-03-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
4IGG
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BU of 4igg by Molmil
Full-length human alpha-catenin crystal structure
分子名称: Catenin alpha-1, PHOSPHATE ION
著者Izard, T, Rangarajan, E.S.
登録日2012-12-17
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Dimer asymmetry defines alpha-catenin interactions.
Nat.Struct.Mol.Biol., 20, 2013
4ONS
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BU of 4ons by Molmil
Structural and thermodynamic characterization of cadherin-beta-catenin-alpha-catenin complex formation
分子名称: Catenin alpha-2, Catenin beta-1
著者Pokutta, S, Choi, H.-J, Ahlsen, G, Hansen, S.D, Weis, W.I.
登録日2014-01-29
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Thermodynamic Characterization of Cadherin beta-Catenin alpha-Catenin Complex Formation.
J.Biol.Chem., 289, 2014
5Y04
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BU of 5y04 by Molmil
Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin
分子名称: Catenin alpha-1, Vinculin
著者Hirano, Y, Hakoshima, T.
登録日2017-07-14
公開日2018-03-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
6DUW
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BU of 6duw by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
分子名称: Catenin alpha-2
著者Ishiyama, N, Ikura, M.
登録日2018-06-22
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
6DUY
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BU of 6duy by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
分子名称: Catenin alpha-2
著者Ishiyama, N, Ikura, M.
登録日2018-06-22
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
4P9T
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BU of 4p9t by Molmil
Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin
分子名称: 1,2-ETHANEDIOL, Catenin alpha-2, DI(HYDROXYETHYL)ETHER, ...
著者Shibahara, T, Hirano, Y, Hakoshima, T.
登録日2014-04-04
公開日2015-04-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin.
Febs Lett., 589, 2015
4K1O
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BU of 4k1o by Molmil
Crystal structure of the alphaN-catenin actin-binding domain
分子名称: Catenin alpha-2, SULFATE ION
著者Ishiyama, N, Ikura, M.
登録日2013-04-05
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions.
J.Biol.Chem., 288, 2013
4PR9
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Human Vinculin (residues 891-1066) in complex with PIP
分子名称: GLYCEROL, Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Chinthalapudi, K, Rangarajan, E.S, Patil, D, Izard, T.
登録日2014-03-05
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanism and function of lipid-directed oligomerization of vinculin
To be Published
4K1N
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BU of 4k1n by Molmil
Crystal structure of full-length mouse alphaE-catenin
分子名称: Catenin alpha-1
著者Ishiyama, N, Ikura, M.
登録日2013-04-05
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions.
J.Biol.Chem., 288, 2013
3TJ5
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BU of 3tj5 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
分子名称: Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin
著者Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
3TJ6
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human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii
分子名称: Antigenic heat-stable 120 kDa protein, Vinculin
著者Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
4DJ9
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Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)
分子名称: Talin-1, Vinculin
著者Yogesha, S.D, Rangarajan, E.S, Vonrhein, C, Bricogne, G, Izard, T.
登録日2012-02-01
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.
Protein Sci., 21, 2012
7KTU
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BU of 7ktu by Molmil
Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 1
分子名称: metavinculin
著者Izard, T, Rangarajan, E.S.
登録日2020-11-24
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021
7KTV
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Cryogenic electron microscopy model of full-length human metavinculin H1' kinked conformation
分子名称: metavinculin
著者Izard, T, Rangarajan, E.S.
登録日2020-11-24
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021

 

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