Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin

Summary for 5Y04

DescriptorVinculin, Catenin alpha-1 (3 entities in total)
Functional Keywordsadherens junction, cytoskeleton, cell adhesion
Biological sourceMus musculus (Mouse)
Cellular locationCell membrane ; Peripheral membrane protein ; Cytoplasmic side  Q64727
Cytoplasm, cytoskeleton P26231
Total number of polymer chains2
Total molecular weight39511.4
Hirano, Y.,Hakoshima, T. (deposition date: 2017-07-14, release date: 2018-03-28, Last modification date: 2018-05-23)
Primary citation
Hirano, Y.,Amano, Y.,Yonemura, S.,Hakoshima, T.
The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23:370-385, 2018
PubMed: 29542234 (PDB entries with the same primary citation)
DOI: 10.1111/gtc.12578
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.281220.7%6.5%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5y04
no rotation
Molmil generated image of 5y04
rotated about x axis by 90°
Molmil generated image of 5y04
rotated about y axis by 90°
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