4PR9

Human Vinculin (residues 891-1066) in complex with PIP

Summary for 4PR9

Related1RKE
DescriptorVinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, GLYCEROL, ... (4 entities in total)
Functional Keywords5-helix bundle, cytoskeletal protein, lipids, cell adhesion, structural protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton  P18206
Total number of polymer chains6
Total molecular weight120559.11
Authors
Chinthalapudi, K.,Rangarajan, E.S.,Patil, D.,Izard, T. (deposition date: 2014-03-05, release date: 2014-12-10)
Primary citation
Chinthalapudi, K.,Rangarajan, E.S.,Patil, D.,Izard, T.
Mechanism and function of lipid-directed oligomerization of vinculin
To be Published,
Experimental method
X-RAY DIFFRACTION (3.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26816007.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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