6DUY

Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant

Summary for 6DUY

Entry DOI	10.2210/pdb6duy/pdb
Descriptor	Catenin alpha-2 (2 entities in total)
Functional Keywords	five-helix bundle, f-actin-binding, mechanosensor, cell adhesion
Biological source	Mus musculus (Mouse)
Total number of polymer chains	2
Total formula weight	56240.68
Authors	Ishiyama, N.,Ikura, M. (deposition date: 2018-06-22, release date: 2018-12-19, Last modification date: 2023-10-11)
Primary citation	Ishiyama, N.,Sarpal, R.,Wood, M.N.,Barrick, S.K.,Nishikawa, T.,Hayashi, H.,Kobb, A.B.,Flozak, A.S.,Yemelyanov, A.,Fernandez-Gonzalez, R.,Yonemura, S.,Leckband, D.E.,Gottardi, C.J.,Tepass, U.,Ikura, M. Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9:5121-5121, 2018 Cited by PubMed: 30504777 DOI: 10.1038/s41467-018-07481-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation