PDB: 14 件ウェブページステータス検索Chemie searchBIRD

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5Z6Z	Crystal structure of human DUX4 homeodomains bound to DNA 分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4 著者 Li, Y.Y, Wu, B.X, Gan, J.H. 登録日 2018-01-26 公開日 2018-10-31 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
6A8R	Crystal structure of DUX4 HD2 domain associated with ERG DNA binding site 分子名称: DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), Double homeobox protein 4 著者 Dong, X, Zhang, H, Cheng, N, Meng, G. 登録日 2018-07-10 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element. Leukemia, 33, 2019
6U82	Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer containing bulge and loop 分子名称: DNA (38-MER), Double homeobox protein 4 著者 Shi, K, Aihara, H. 登録日 2019-09-04 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD. Faseb J., 34, 2020
6E8C	Crystal structure of the double homeodomain of DUX4 in complex with DNA 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), Double homeobox protein 4 著者 Lee, J.K, Bosnakovski, D, Toso, E.A, Dinh, T, Banerjee, S, Bohl, T.E, Shi, K, Kurahashi, K, Kyba, M, Aihara, H. 登録日 2018-07-27 公開日 2018-12-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA. Cell Rep, 25, 2018
6U81	Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*CP*CP*CP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Shi, K, Aihara, H. 登録日 2019-09-04 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD. Faseb J., 34, 2020
5Z2S	Crystal structure of DUX4-HD2 domain 分子名称: Double homeobox protein 4 著者 Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. 登録日 2018-01-03 公開日 2018-04-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
5Z2T	Crystal structure of DNA-bound DUX4-HD2 分子名称: 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3', Double homeobox protein 4 著者 Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. 登録日 2018-01-04 公開日 2018-04-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
6DFY	Remodeled crystal structure of DNA-bound DUX4-HD2 分子名称: DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), Double homeobox protein 4 著者 Aihara, H, Shi, K. 登録日 2018-05-15 公開日 2018-09-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Comment on structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
5ZFZ	Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant 分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 著者 Li, Y.Y, Wu, B.X, Gan, J.H. 登録日 2018-03-07 公開日 2018-10-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
5ZFW	Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant 分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 著者 Li, Y.Y, Wu, B.X, Gan, J.H. 登録日 2018-03-07 公開日 2018-10-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
5ZFY	Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant 分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 著者 Li, Y.Y, Wu, B.X, Gan, J.H. 登録日 2018-03-07 公開日 2018-10-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
7DW5	Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites 分子名称: BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 著者 Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. 登録日 2021-01-15 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia. Cancer Commun (Lond), 41, 2021
8EJO	Crystal structure of the homeodomain of Platypus sDUX in complex with DNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Yin, L, Shi, K, Aihara, H. 登録日 2022-09-18 公開日 2023-09-20 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. Iscience, 26, 2023
8EJP	Crystal structure of the homeodomain of Platypus sDUX in complex with DNA containing 5-Bromouracil 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Yin, L, Shi, K, Aihara, H. 登録日 2022-09-18 公開日 2023-09-20 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (2.174 Å) 主引用文献 Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. Iscience, 26, 2023