6DFY

Remodeled crystal structure of DNA-bound DUX4-HD2

Summary for 6DFY

• Entry DOI: 10.2210/pdb6dfy/pdb
• Descriptor: Double homeobox protein 4, DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), ... (4 entities in total)
• Functional Keywords: dux4-responsive-element, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 23129.23

Authors

Aihara, H.,Shi, K. (deposition date: 2018-05-15, release date: 2018-09-05, Last modification date: 2023-10-11)

• Primary citation: Aihara, H.,Shi, K.,Lee, J.K.,Bosnakovski, D.,Kyba, M.; Comment on structural basis of DUX4/IGH-driven transactivation.; Leukemia, 32:2090-2092, 2018; PubMed: 30054554; DOI: 10.1038/s41375-018-0217-7

Experimental method

X-RAY DIFFRACTION (2.623 Å)