6DFY

Remodeled crystal structure of DNA-bound DUX4-HD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, D	Double homeobox protein 4	polymer	64	7286.3	2	UniProt (Q9UBX2) Pfam (PF00046) In PDB	Homo sapiens (Human)	Double homeobox protein 10
2	E	DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3')	polymer	14	4342.9	1		synthetic construct
3	F	DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3')	polymer	14	4213.8	1		synthetic construct
4		water	water		18.0	12	Chemie (HOH)

Sequence modifications

C, D: 5 - 64 (UniProt: Q9UBX2)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	23129.2
All*	Total formula weight	23129.2

*Water molecules are not included.