6DFY
Remodeled crystal structure of DNA-bound DUX4-HD2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (C, D) | Double homeobox protein 4 | polymer | 64 | 7286.3 | 2 | UniProt (Q9UBX2) Pfam (PF00046) | Homo sapiens (Human) | Double homeobox protein 10 |
| 2 | B (E) | DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3') | polymer | 14 | 4342.9 | 1 | synthetic construct | ||
| 3 | C (F) | DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3') | polymer | 14 | 4213.8 | 1 | synthetic construct | ||
| 4 | E, F, G, H (C, E, F, D) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
C, D: 5 - 64 (UniProt: Q9UBX2)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| His 3 | - | expression tag |
| Met 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 23129.2 | |
| All* | Total formula weight | 23129.2 |
