5Z2S

Crystal structure of DUX4-HD2 domain

Summary for 5Z2S

• Entry DOI: 10.2210/pdb5z2s/pdb
• Descriptor: Double homeobox protein 4 (2 entities in total)
• Functional Keywords: acute lymphoblastic leukemia, dux4/igh, dux4-responsive-element, transactivation, ergalt, dna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 6285.15

Authors

Dong, X.,Zhang, W.,Wu, H.,Huang, J.,Zhang, M.,Wang, P.,Zhang, H.,Chen, Z.,Chen, S.,Meng, G. (deposition date: 2018-01-03, release date: 2018-04-04, Last modification date: 2023-11-22)

• Primary citation: Dong, X.,Zhang, W.,Wu, H.,Huang, J.,Zhang, M.,Wang, P.,Zhang, H.,Chen, Z.,Chen, S.J.,Meng, G.; Structural basis of DUX4/IGH-driven transactivation.; Leukemia, 32:1466-1476, 2018; PubMed: 29572508; DOI: 10.1038/s41375-018-0093-1

Experimental method

X-RAY DIFFRACTION (1.5 Å)