8EJP

Crystal structure of the homeodomain of Platypus sDUX in complex with DNA containing 5-Bromouracil

Summary for 8EJP

• Entry DOI: 10.2210/pdb8ejp/pdb
• Descriptor: Homeobox domain-containing protein, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... (5 entities in total)
• Functional Keywords: dux4, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Ornithorhynchus anatinus (platypus); More
• Total number of polymer chains: 4
• Total formula weight: 27204.09

Authors

Yin, L.L.,Shi, K.,Aihara, H. (deposition date: 2022-09-18, release date: 2023-09-20, Last modification date: 2023-10-04)

• Primary citation: Bosnakovski, D.,Toso, E.A.,Ener, E.T.,Gearhart, M.D.,Yin, L.,Luttmann, F.F.,Magli, A.,Shi, K.,Kim, J.,Aihara, H.,Kyba, M.; Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.; Iscience, 26:107823-107823, 2023; PubMed: 37744032; DOI: 10.1016/j.isci.2023.107823

Experimental method

X-RAY DIFFRACTION (2.174 Å)