PDB: 2602 件ウェブページステータス検索Chemie searchBIRD

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7X1T	Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin. 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... 著者 Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. 登録日 2022-02-24 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
7XBD	Cryo-EM structure of human galanin receptor 2 分子名称: Galanin, Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ishimoto, N, Kita, S, Park, S.Y. 登録日 2022-03-21 公開日 2022-07-13 最終更新日 2022-08-10 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface. Plos Biol., 20, 2022
7XBW	Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1 分子名称: CHOLESTEROL, CX3C chemokine receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Lu, M, Zhao, W, Han, S, Zhu, Y, Wu, B, Zhao, Q. 登録日 2022-03-22 公開日 2022-07-13 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Sci Adv, 8, 2022
7X5H	Serotonin 5A (5-HT5A) receptor-Gi protein complex 分子名称: 3-(2-azanylethyl)-1H-indole-5-carboxamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Tan, Y, Xu, P, Huang, S, Xu, H.E, Jiang, Y. 登録日 2022-03-04 公開日 2022-09-14 最終更新日 2022-09-21 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into the ligand binding and G i coupling of serotonin receptor 5-HT 5A . Cell Discov, 8, 2022
7XK2	Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex 分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, DiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. 登録日 2022-04-19 公開日 2023-02-22 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14, 2023
7XK8	Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Zhao, W, Wenru, Z, Mu, W, Minmin, L, Shutian, C, Tingting, T, Gisela, S, Holger, W, Albert, B, Cuiying, Y, Xiaojing, C, Han, S, Wu, B, Zhao, Q. 登録日 2022-04-19 公開日 2023-02-22 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Ligand recognition and activation of neuromedin U receptor 2. Nat Commun, 13, 2022
7Y35	Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex 分子名称: Abaloparatide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Zhai, X, Mao, C, Shen, Q, Zang, S, Shen, D, Zhang, H, Chen, Z, Wang, G, Zhang, C, Zhang, Y, Liu, Z. 登録日 2022-06-09 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex To Be Published
7Y36	Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Zhai, X, Mao, C, Shen, Q, Zang, S, Shen, D, Zhang, H, Chen, Z, Wang, G, Zhang, C, Zhang, Y, Liu, Z. 登録日 2022-06-10 公開日 2023-07-05 最終更新日 2024-09-25 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex to be published
7XZ5	GPR119-Gs-LPC complex 分子名称: (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Xu, P, Huang, S, Jiang, Y, Xu, H.E. 登録日 2022-06-02 公開日 2022-08-24 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119. Nat.Struct.Mol.Biol., 29, 2022
7XZ6	GPR119-Gs-APD668 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Xu, P, Huang, S, Jiang, Y, Xu, H.E. 登録日 2022-06-02 公開日 2022-08-24 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119. Nat.Struct.Mol.Biol., 29, 2022
7XW5	TSHR-thyroid stimulating hormone-Gs-ML109 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Glycoprotein hormones alpha chain, ... 著者 Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. 登録日 2022-05-26 公開日 2022-08-24 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
7XJJ	Cryo-EM structure of the galanin-bound GALR1-miniGo complex 分子名称: G protein subunit alpha o1,Guanine nucleotide-binding protein G(o) subunit alpha, Galanin, Galanin receptor type 1, ... 著者 Jiang, W, Zheng, S. 登録日 2022-04-18 公開日 2023-05-03 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural insights into galanin receptor signaling. Proc.Natl.Acad.Sci.USA, 119, 2022
7WZ7	GPR110/G12 complex 分子名称: Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 He, Y, Zhu, X. 登録日 2022-02-17 公開日 2022-09-28 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
7WXU	GPR110/Gq complex 分子名称: Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 He, Y, Zhu, X. 登録日 2022-02-15 公開日 2022-09-28 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
7WY0	GPR110/G13 complex 分子名称: Adhesion G-protein coupled receptor F1, Engineered G alpha 13 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 He, Y, Zhu, X. 登録日 2022-02-15 公開日 2022-09-28 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
7XBX	Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Lu, M, Zhao, W, Han, S, Zhu, Y, Wu, B, Zhao, Q. 登録日 2022-03-22 公開日 2022-07-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Sci Adv, 8, 2022
7WXW	GPR110/Gs complex 分子名称: Adhesion G-protein coupled receptor F1, Engineered mini Galpha-s subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 He, Y, Zhu, X. 登録日 2022-02-15 公開日 2022-09-28 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
7X2V	GPR110/Gi complex 分子名称: Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 He, Y, Zhu, X. 登録日 2022-02-26 公開日 2022-09-28 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
7XOU	Structural insights into human brain gut peptide cholecystokinin receptors 分子名称: CCK-8, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. 登録日 2022-05-01 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into human brain-gut peptide cholecystokinin receptors. Cell Discov, 8, 2022
7XOV	Structural insights into human brain gut peptide cholecystokinin receptors 分子名称: 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5,7-dimethyl-indol-1-yl]ethanoic acid, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. 登録日 2022-05-01 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into human brain-gut peptide cholecystokinin receptors. Cell Discov, 8, 2022
7XOW	Structural insights into human brain gut peptide cholecystokinin receptors 分子名称: Gastrin, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. 登録日 2022-05-01 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into human brain-gut peptide cholecystokinin receptors. Cell Discov, 8, 2022
7W57	Cryo-EM structure of the neuromedin S-bound neuromedin U receptor 2-Gq protein complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... 著者 You, C, Xu, H.E, Jiang, Y. 登録日 2021-11-29 公開日 2022-04-20 最終更新日 2022-06-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
7W56	Cryo-EM structure of the neuromedin S-bound neuromedin U receptor 1-Gq protein complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... 著者 You, C, Xu, H.E, Jiang, Y. 登録日 2021-11-29 公開日 2022-04-20 最終更新日 2022-12-07 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
7WQ4	Galanin-bound galanin receptor 2 in complex with Gq 分子名称: CHOLESTEROL, Engineered Guanine nucleotide-binding protein G(q) subunit alpha, Galanin, ... 著者 Duan, J, Shen, D.D, Xu, H.E, Zhang, Y, Jiang, Y. 登録日 2022-01-24 公開日 2022-04-20 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors Nat Commun, 13, 2022
7WQ3	Galanin-bound galanin receptor 1 in complex with Gi 分子名称: CHOLESTEROL, Galanin, Galanin receptor type 1, ... 著者 Duan, J, Shen, D.D, Xu, H.E, Zhang, Y, Jiang, Y. 登録日 2022-01-24 公開日 2022-04-20 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors Nat Commun, 13, 2022

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