7WQ4

Galanin-bound galanin receptor 2 in complex with Gq

Summary for 7WQ4

Entry DOI	10.2210/pdb7wq4/pdb
EMDB information	32699
Descriptor	Galanin receptor type 2, Galanin, Engineered Guanine nucleotide-binding protein G(q) subunit alpha, ... (7 entities in total)
Functional Keywords	gpcr, galanin receptor 2, galanin, gq, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	147379.61
Authors	Duan, J.,Shen, D.D.,Xu, H.E.,Zhang, Y.,Jiang, Y. (deposition date: 2022-01-24, release date: 2022-04-20, Last modification date: 2024-11-20)
Primary citation	Duan, J.,Shen, D.D.,Zhao, T.,Guo, S.,He, X.,Yin, W.,Xu, P.,Ji, Y.,Chen, L.N.,Liu, J.,Zhang, H.,Liu, Q.,Shi, Y.,Cheng, X.,Jiang, H.,Eric Xu, H.,Zhang, Y.,Xie, X.,Jiang, Y. Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors Nat Commun, 13:1364-, 2022 Cited by DOI: 10.1038/s41467-022-29072-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation