7WQ4

Galanin-bound galanin receptor 2 in complex with Gq

Summary for 7WQ4

• Entry DOI: 10.2210/pdb7wq4/pdb
• EMDB information: 32699
• Descriptor: Galanin receptor type 2, Galanin, Engineered Guanine nucleotide-binding protein G(q) subunit alpha, ... (7 entities in total)
• Functional Keywords: gpcr, galanin receptor 2, galanin, gq, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 147379.61

Authors

Duan, J.,Shen, D.D.,Xu, H.E.,Zhang, Y.,Jiang, Y. (deposition date: 2022-01-24, release date: 2022-04-20, Last modification date: 2022-10-19)

• Primary citation: Duan, J.,Shen, D.D.,Zhao, T.,Guo, S.,He, X.,Yin, W.,Xu, P.,Ji, Y.,Chen, L.N.,Liu, J.,Zhang, H.,Liu, Q.,Shi, Y.,Cheng, X.,Jiang, H.,Eric Xu, H.,Zhang, Y.,Xie, X.,Jiang, Y.; Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors; Nat Commun, 13:1364-, 2022; DOI: 10.1038/s41467-022-29072-3

Experimental method

ELECTRON MICROSCOPY (2.6 Å)