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7XK2

Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex

Summary for 7XK2
Entry DOI10.2210/pdb7xk2/pdb
EMDB information33241
DescriptorGuanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hydroxycarboxylic acid receptor 2, ... (6 entities in total)
Functional Keywordsniacin receptor, hydroxycarboxylic acid receptor 2, hca2, gi complex, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains5
Total formula weight150700.38
Authors
Primary citationYang, Y.,Kang, H.J.,Gao, R.,Wang, J.,Han, G.W.,DiBerto, J.F.,Wu, L.,Tong, J.,Qu, L.,Wu, Y.,Pileski, R.,Li, X.,Zhang, X.C.,Zhao, S.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.,Liu, Z.J.
Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14:1692-1692, 2023
Cited by
PubMed: 36973264
DOI: 10.1038/s41467-023-37177-6
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

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