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8IW1
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BU of 8iw1 by Molmil
Cryo-EM structure of the PEA-bound mTAAR9-Golf complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(olf) subunit alpha, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-29
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IUM
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BU of 8ium by Molmil
Cryo-EM structure of the tafluprost acid-bound human PTGFR-Gq complex
分子名称: (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E})-3,3-bis(fluoranyl)-4-phenoxy-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, G subunit alpha (q), ...
著者Wu, C, Xu, Y, Xu, H.E.
登録日2023-03-24
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Ligand-induced activation and G protein coupling of prostaglandin F 2 alpha receptor.
Nat Commun, 14, 2023
8IUL
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BU of 8iul by Molmil
Cryo-EM structure of the latanoprost-bound human PTGFR-Gq complex
分子名称: Antibody fragment scFv16, G subunit alpha (q), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Wu, C, Xu, Y, Xu, H.E.
登録日2023-03-24
公開日2023-07-12
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Ligand-induced activation and G protein coupling of prostaglandin F 2 alpha receptor.
Nat Commun, 14, 2023
8IUK
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BU of 8iuk by Molmil
Cryo-EM structure of the PGF2-alpha-bound human PTGFR-Gq complex
分子名称: (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, G subunit alpha (q), ...
著者Wu, C, Xu, Y, Xu, H.E.
登録日2023-03-24
公開日2023-07-12
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Ligand-induced activation and G protein coupling of prostaglandin F 2 alpha receptor.
Nat Commun, 14, 2023
8IU2
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BU of 8iu2 by Molmil
Cryo-EM structure of Long-wave-sensitive opsin 1
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Peng, Q, Cheng, X.Y, Li, J, Lu, Q.Y, Li, Y.Y, Zhang, J.
登録日2023-03-23
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cryo-EM structure of Long-wave-sensitive opsin 1
To Be Published
8ITM
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BU of 8itm by Molmil
Cryo-EM structure of GIPR splice variant 2 (SV2) in complex with Gs protein
分子名称: Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhao, F.H, Hang, K.N, Zhou, Q.T, Shao, L.J, Li, H, Li, W.Z, Lin, S, Dai, A.T, Cai, X.Q, Liu, Y.Y, Xu, Y.N, Feng, W.B, Yang, D.H, Wang, M.W.
登録日2023-03-22
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Molecular basis of signal transduction mediated by the human GIPR splice variants.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ITL
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BU of 8itl by Molmil
Cryo-EM structure of GIPR splice variant 1 (SV1) in complex with Gs protein
分子名称: Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhao, F.H, Hang, K.N, Zhou, Q.T, Shao, L.J, Li, H, Li, W.Z, Lin, S, Dai, A.T, Cai, X.Q, Liu, Y.Y, Xu, Y.N, Feng, W.B, Yang, D.H, Wang, M.W.
登録日2023-03-22
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Molecular basis of signal transduction mediated by the human GIPR splice variants.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ITF
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BU of 8itf by Molmil
Cryo-EM structure of the DMCHA-bound mTAAR9-Gs complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-22
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IRV
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BU of 8irv by Molmil
Dopamine Receptor D5R-Gs-Rotigotine complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-07
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRU
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BU of 8iru by Molmil
Dopamine Receptor D4R-Gi-Rotigotine complex
分子名称: CHOLESTEROL, D(4) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-21
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRT
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BU of 8irt by Molmil
Dopamine Receptor D3R-Gi-Rotigotine complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-07
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRS
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BU of 8irs by Molmil
Dopamine Receptor D2R-Gi-Rotigotine complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-07
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRR
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BU of 8irr by Molmil
Dopamine Receptor D1R-Gs-Rotigotine complex
分子名称: CHOLESTEROL, D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-21
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IQ6
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BU of 8iq6 by Molmil
Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X.
登録日2023-03-15
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
8IQ4
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BU of 8iq4 by Molmil
Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X.
登録日2023-03-15
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
8IOD
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BU of 8iod by Molmil
Cryo-EM structure of the PG-901-bound human melanocortin receptor 5 (MC5R)-Gs complex
分子名称: CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ...
著者Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S, Yang, D.H, Wang, M.W.
登録日2023-03-10
公開日2023-09-20
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Cell Discov, 9, 2023
8IOC
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BU of 8ioc by Molmil
Cryo-EM structure of the gamma-MSH-bound human melanocortin receptor 3 (MC3R)-Gs complex
分子名称: CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ...
著者Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S.
登録日2023-03-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Cell Discov, 9, 2023
8INR
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BU of 8inr by Molmil
Cryo-EM structure of the alpha-MSH-bound human melanocortin receptor 5 (MC5R)-Gs complex
分子名称: CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ...
著者Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S, Yang, D.H, Wang, M.W.
登録日2023-03-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Cell Discov, 9, 2023
8IKL
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BU of 8ikl by Molmil
Cryo-EM structure of the CD97-G13 complex
分子名称: Adhesion G protein-coupled receptor E5, Guanine nucleotide-binding protein G(13) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P.
登録日2023-02-28
公開日2024-01-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Conformational transitions and activation of the adhesion receptor CD97.
Mol.Cell, 84, 2024
8IJD
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BU of 8ijd by Molmil
Cryo-EM structure of human HCAR2-Gi complex with MK-6892
分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-27
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJB
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BU of 8ijb by Molmil
Cryo-EM structure of human HCAR2-Gi complex with acipimox
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-27
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJA
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BU of 8ija by Molmil
Cryo-EM structure of human HCAR2-Gi complex with niacin
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-26
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJ3
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BU of 8ij3 by Molmil
Cryo-EM structure of human HCAR2-Gi complex without ligand (apo state)
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-24
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IHJ
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BU of 8ihj by Molmil
Cryo-EM structure of HCA3-Gi complex with acifran
分子名称: (5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
登録日2023-02-22
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
8IHI
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BU of 8ihi by Molmil
Cryo-EM structure of HCA2-Gi complex with acifran
分子名称: (5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
登録日2023-02-22
公開日2023-08-30
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023

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