8IUK
Cryo-EM structure of the PGF2-alpha-bound human PTGFR-Gq complex
Summary for 8IUK
Entry DOI | 10.2210/pdb8iuk/pdb |
EMDB information | 35724 |
Descriptor | G subunit alpha (q), Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Antibody fragment scFv16, ... (7 entities in total) |
Functional Keywords | gpcr, ptgfr, pgf2-alpha, gq, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 170182.36 |
Authors | |
Primary citation | Wu, C.,Xu, Y.,He, Q.,Li, D.,Duan, J.,Li, C.,You, C.,Chen, H.,Fan, W.,Jiang, Y.,Eric Xu, H. Ligand-induced activation and G protein coupling of prostaglandin F 2 alpha receptor. Nat Commun, 14:2668-2668, 2023 Cited by PubMed: 37160891DOI: 10.1038/s41467-023-38411-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.67 Å) |
Structure validation
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