8IJA

Cryo-EM structure of human HCAR2-Gi complex with niacin

Summary for 8IJA

Entry DOI	10.2210/pdb8ija/pdb
EMDB information	35483
Descriptor	Hydroxycarboxylic acid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	complex, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	144240.84
Authors	Pan, X.,Fang, Y. (deposition date: 2023-02-26, release date: 2024-01-03)
Primary citation	Pan, X.,Ye, F.,Ning, P.,Zhang, Z.,Li, X.,Zhang, B.,Wang, Q.,Chen, G.,Gao, W.,Qiu, C.,Wu, Z.,Li, J.,Zhu, L.,Xia, J.,Gong, K.,Du, Y. Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2. Cell Discov, 9:118-118, 2023 Cited by PubMed: 38012147 DOI: 10.1038/s41421-023-00610-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.69 Å)

Structure validation