8ITF

Cryo-EM structure of the DMCHA-bound mTAAR9-Gs complex

Summary for 8ITF

Entry DOI	10.2210/pdb8itf/pdb
EMDB information	35705
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
Functional Keywords	dmcha, mtaar9, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	172745.81
Authors	Sun, J.P.,Li, Q.,Yang, F.,Xu, Y.F.,Guo, L.L.,Lian, S.,Zhang, M.H.,Rong, N.K. (deposition date: 2023-03-22, release date: 2023-05-31, Last modification date: 2023-06-14)
Primary citation	Guo, L.,Cheng, J.,Lian, S.,Liu, Q.,Lu, Y.,Zheng, Y.,Zhu, K.,Zhang, M.,Kong, Y.,Zhang, C.,Rong, N.,Zhuang, Y.,Fang, G.,Jiang, J.,Zhang, T.,Han, X.,Liu, Z.,Xia, M.,Liu, S.,Zhang, L.,Liberles, S.D.,Yu, X.,Xu, Y.,Yang, F.,Li, Q.,Sun, J.P. Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618:193-200, 2023 Cited by PubMed: 37225986 DOI: 10.1038/s41586-023-06106-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.46 Å)

Structure validation