PDB: 888 件ウェブページステータス検索Chemie searchBIRD

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6OIK	Muscarinic acetylcholine receptor 2-Go complex 分子名称: 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Antibody fragment, ... 著者 Maeda, S, Qianhui, Q, Skiniotis, G, Kobilka, B. 登録日 2019-04-09 公開日 2019-05-08 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes. Science, 364, 2019
6ORV	Non-peptide agonist (TT-OAD2) bound to the Glucagon-Like peptide-1 (GLP-1) Receptor 分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Belousoff, M.J, Liang, Y.L, Danev, R. 登録日 2019-05-01 公開日 2020-01-08 最終更新日 2020-01-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Activation of the GLP-1 receptor by a non-peptidic agonist. Nature, 577, 2020
6OMM	Cryo-EM structure of formyl peptide receptor 2/lipoxin A4 receptor in complex with Gi 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Zhuang, Y, Liu, H, de Waal, P.W, Zhou, X.E, Wang, L, Meng, X, Zhao, G, Kang, Y, Melcher, K, Xu, H.E, Zhang, C. 登録日 2019-04-19 公開日 2020-02-26 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 Structure of formylpeptide receptor 2-Gicomplex reveals insights into ligand recognition and signaling. Nat Commun, 11, 2020
6OY9	Structure of the Rhodopsin-Transducin Complex 分子名称: Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... 著者 Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. 登録日 2019-05-14 公開日 2019-07-24 最終更新日 2019-12-04 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Mol.Cell, 75, 2019
6PB0	Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35 分子名称: CHOLESTEROL, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. 登録日 2019-06-12 公開日 2020-02-12 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
6P9X	CRF1 Receptor Gs GPCR protein complex with CRF1 peptide 分子名称: Corticoliberin, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. 登録日 2019-06-10 公開日 2020-02-05 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Mol.Cell, 77, 2020
6P9Y	PAC1 GPCR Receptor complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. 登録日 2019-06-10 公開日 2020-02-05 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Mol.Cell, 77, 2020
1CS4	COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2'-DEOXY-ADENOSINE 3'-MONOPHOSPHATE, PYROPHOSPHATE AND MG 分子名称: 2'-DEOXY-ADENOSINE 3'-MONOPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... 著者 Tesmer, J.J.G, Dessauer, C.A, Sunahara, R.K, Johnson, R.A, Gilman, A.G, Sprang, S.R. 登録日 1999-08-16 公開日 2001-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis for P-site inhibition of adenylyl cyclase. Biochemistry, 39, 2000
6PB1	Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 分子名称: CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. 登録日 2019-06-12 公開日 2020-02-12 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
1CJU	COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH BETA-L-2',3'-DIDEOXYATP AND MG 分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADENYLATE CYCLASE, ... 著者 Tesmer, J.J.G, Sprang, S.R. 登録日 1999-04-16 公開日 1999-08-31 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Two-metal-Ion catalysis in adenylyl cyclase. Science, 285, 1999
1CUL	COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2',5'-DIDEOXY-ADENOSINE 3'-TRIPHOSPHATE AND MG 分子名称: 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... 著者 Tesmer, J.J.G, Dessauer, C.A, Sunahara, R.K, Johnson, R.A, Gilman, A.G, Sprang, S.R. 登録日 1999-08-20 公開日 2001-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for P-site inhibition of adenylyl cyclase. Biochemistry, 39, 2000
6PT0	Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2 分子名称: CHOLESTEROL, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Xu, T.H, Xing, C, Zhuang, Y, Feng, Z, Zhou, X.E, Chen, M, Wang, L, Meng, X, Xue, Y, Wang, J, Liu, H, McGuire, T, Zhao, G, Melcher, K, Zhang, C, Xu, H.E, Xie, X.Q. 登録日 2019-07-14 公開日 2020-02-12 最終更新日 2020-03-04 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex. Cell, 180, 2020
1GG2	G PROTEIN HETEROTRIMER MUTANT GI_ALPHA_1(G203A) BETA_1 GAMMA_2 WITH GDP BOUND 分子名称: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ... 著者 Wall, M.A, Sprang, S.R. 登録日 1996-11-13 公開日 1997-02-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell(Cambridge,Mass.), 83, 1995
1GOT	HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS 分子名称: GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ... 著者 Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B. 登録日 1996-08-07 公開日 1997-03-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The 2.0 A crystal structure of a heterotrimeric G protein. Nature, 379, 1996
1GP2	G PROTEIN HETEROTRIMER GI_ALPHA_1 BETA_1 GAMMA_2 WITH GDP BOUND 分子名称: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ... 著者 Wall, M.A, Sprang, S.R. 登録日 1996-11-13 公開日 1997-02-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell(Cambridge,Mass.), 83, 1995
6LI3	cryo-EM structure of GPR52-miniGs-NB35 分子名称: G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Li, M, Wang, N, Xu, F, Wu, J, Lei, M. 登録日 2019-12-10 公開日 2020-02-26 最終更新日 2020-03-18 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Structural basis of ligand recognition and self-activation of orphan GPR52. Nature, 579, 2020
6LML	Cryo-EM structure of the human glucagon receptor in complex with Gi1 分子名称: Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. 登録日 2019-12-26 公開日 2020-04-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
6LPB	Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Kobayashi, K, Shihoya, W, Nishizawa, T, Nureki, O. 登録日 2020-01-09 公開日 2020-03-11 最終更新日 2020-03-25 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nat.Struct.Mol.Biol., 27, 2020
6LMK	Cryo-EM structure of the human glucagon receptor in complex with Gs 分子名称: Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Qiao, A, Han, S, Tai, L, Sun, F, Zhao, Q, Wu, B. 登録日 2019-12-26 公開日 2020-04-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
6M1I	CryoEM structure of human PAC1 receptor in complex with PACAP38 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. 登録日 2020-02-26 公開日 2020-03-11 最終更新日 2020-05-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
6NBI	Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein 分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. 登録日 2018-12-07 公開日 2019-04-17 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
6NI3	B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex 分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. 登録日 2018-12-26 公開日 2019-11-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
6NIY	A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex 分子名称: Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M. 登録日 2019-01-02 公開日 2019-01-23 最終更新日 2020-04-08 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2, 2019
6NBH	Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein 分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. 登録日 2018-12-07 公開日 2019-04-17 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
6M1H	CryoEM structure of human PAC1 receptor in complex with maxadilan 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. 登録日 2020-02-26 公開日 2020-03-11 最終更新日 2020-05-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020

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