1CJU

COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH BETA-L-2',3'-DIDEOXYATP AND MG

Summary for 1CJU

DescriptorADENYLATE CYCLASE, TYPE V, ADENYLATE CYCLASE, TYPE II, GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ... (9 entities in total)
Functional Keywordscomplex (lyase-hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase-lyase-signaling protein complex, lyase/lyase/signaling protein
Biological sourceCanis lupus (dog)
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Cellular locationMembrane; Multi-pass membrane protein P30803 P26769
Cell membrane; Lipid-anchor (By similarity) P04896
Total number of polymer chains3
Total molecular weight96402.13
Authors
Tesmer, J.J.G.,Sprang, S.R. (deposition date: 1999-04-16, release date: 1999-08-31, Last modification date: 2011-07-13)
Primary citation
Tesmer, J.J.,Sunahara, R.K.,Johnson, R.A.,Gosselin, G.,Gilman, A.G.,Sprang, S.R.
Two-metal-Ion catalysis in adenylyl cyclase.
Science, 285:756-760, 1999
PubMed: 10427002 (PDB entries with the same primary citation)
DOI: 10.1126/science.285.5428.756
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28170.4%2.1%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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