6NIY
A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex
Summary for 6NIY
Entry DOI | 10.2210/pdb6niy/pdb |
EMDB information | 8623 9382 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Nanobody35, Calcitonin receptor, ... (6 entities in total) |
Functional Keywords | gpcr, transmembrane, receptor, calcitonin, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 164970.54 |
Authors | dal Maso, E.,Glukhova, A.,Zhu, Y.,Garcia-Nafria, J.,Tate, C.G.,Atanasio, S.,Reynolds, C.A.,Ramirez-Aportela, E.,Carazo, J.-M.,Hick, C.A.,Furness, S.G.B.,Hay, D.L.,Liang, Y.-L.,Miller, L.J.,Christopoulos, A.,Wang, M.-W.,Wootten, D.,Sexton, P.M. (deposition date: 2019-01-02, release date: 2019-01-23, Last modification date: 2020-04-08) |
Primary citation | Dal Maso, E.,Glukhova, A.,Zhu, Y.,Garcia-Nafria, J.,Tate, C.G.,Atanasio, S.,Reynolds, C.A.,Ramirez-Aportela, E.,Carazo, J.M.,Hick, C.A.,Furness, S.G.B.,Hay, D.L.,Liang, Y.L.,Miller, L.J.,Christopoulos, A.,Wang, M.W.,Wootten, D.,Sexton, P.M. The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2:31-51, 2019 Cited by PubMed: 32219215DOI: 10.1021/acsptsci.8b00056 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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