6LMK
Cryo-EM structure of the human glucagon receptor in complex with Gs
Summary for 6LMK
Entry DOI | 10.2210/pdb6lmk/pdb |
EMDB information | 0917 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | glucagon receptor, gpcr, gs protein, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 159314.58 |
Authors | |
Primary citation | Qiao, A.,Han, S.,Li, X.,Li, Z.,Zhao, P.,Dai, A.,Chang, R.,Tai, L.,Tan, Q.,Chu, X.,Ma, L.,Thorsen, T.S.,Reedtz-Runge, S.,Yang, D.,Wang, M.W.,Sexton, P.M.,Wootten, D.,Sun, F.,Zhao, Q.,Wu, B. Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367:1346-1352, 2020 Cited by PubMed: 32193322DOI: 10.1126/science.aaz5346 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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