6P9X

CRF1 Receptor Gs GPCR protein complex with CRF1 peptide

Summary for 6P9X

• Entry DOI: 10.2210/pdb6p9x/pdb
• EMDB information: 20277
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 161392.95

Authors

Belousoff, M.J.,Liang, Y.L.,Sexton, P.,Danev, R. (deposition date: 2019-06-10, release date: 2020-02-05, Last modification date: 2020-02-19)

• Primary citation: Liang, Y.L.,Belousoff, M.J.,Zhao, P.,Koole, C.,Fletcher, M.M.,Truong, T.T.,Julita, V.,Christopoulos, G.,Xu, H.E.,Zhang, Y.,Khoshouei, M.,Christopoulos, A.,Danev, R.,Sexton, P.M.,Wootten, D.; Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.; Mol.Cell, 77:656-668.e5, 2020; PubMed: 32004469; DOI: 10.1016/j.molcel.2020.01.012

Experimental method

ELECTRON MICROSCOPY (2.91 Å)