1CUL

COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2',5'-DIDEOXY-ADENOSINE 3'-TRIPHOSPHATE AND MG

Summary for 1CUL

Related1CS4
DescriptorTYPE V ADENYLYL CYCLASE, TYPE II ADENYLYL CYCLASE, GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ... (11 entities in total)
Functional Keywordscomplex (lyase-hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase-hydrolase complex, lyase/lyase/signaling protein, lyase-lyase-signaling protein complex
Biological sourceCanis lupus familiaris (dog)
More
Cellular locationMembrane; Multi-pass membrane protein P30803 P26769
Cell membrane; Lipid-anchor (By similarity) P04896
Total number of polymer chains3
Total molecular weight94123.15
Authors
Tesmer, J.J.G.,Dessauer, C.A.,Sunahara, R.K.,Johnson, R.A.,Gilman, A.G.,Sprang, S.R. (deposition date: 1999-08-20, release date: 2001-01-10, Last modification date: 2011-07-13)
Primary citation
Tesmer, J.J.,Dessauer, C.W.,Sunahara, R.K.,Murray, L.D.,Johnson, R.A.,Gilman, A.G.,Sprang, S.R.
Molecular basis for P-site inhibition of adenylyl cyclase.
Biochemistry, 39:14464-14471, 2000
PubMed: 11087399 (PDB entries with the same primary citation)
DOI: 10.1021/bi0015562
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2535 0.4% 1.1% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25