6SNT
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![BU of 6snt by Molmil](/molmil-images/mine/6snt) | Yeast 80S ribosome stalled on SDD1 mRNA. | 分子名称: | 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S10-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R. | 登録日 | 2019-08-27 | 公開日 | 2020-03-04 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Nat.Struct.Mol.Biol., 27, 2020
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8GQR
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![BU of 8gqr by Molmil](/molmil-images/mine/8gqr) | Crystal structure of VioD with FAD | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | 著者 | Ran, T, Wang, W, Xu, M. | 登録日 | 2022-08-30 | 公開日 | 2023-03-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway. Proteins, 91, 2023
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5R0V
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![BU of 5r0v by Molmil](/molmil-images/mine/5r0v) | PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 09, DMSO-free | 分子名称: | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | 著者 | Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. | 登録日 | 2020-02-12 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
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5R1A
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![BU of 5r1a by Molmil](/molmil-images/mine/5r1a) | PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 25, DMSO-free | 分子名称: | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | 著者 | Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. | 登録日 | 2020-02-12 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
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7OX8
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![BU of 7ox8 by Molmil](/molmil-images/mine/7ox8) | Target-bound SpCas9 complex with TRAC full RNA guide | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P. | 登録日 | 2021-06-22 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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7FAU
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![BU of 7fau by Molmil](/molmil-images/mine/7fau) | Structure Determination of the NB1B11-RBD Complex | 分子名称: | NB_1B11, Spike protein S1, ZINC ION | 著者 | Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X. | 登録日 | 2021-07-07 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural basis of nanobodies neutralizing SARS-CoV-2 variants. Structure, 30, 2022
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7TJQ
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![BU of 7tjq by Molmil](/molmil-images/mine/7tjq) | SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | 著者 | Hsieh, C.-L, McLellan, J.S, Rush, S.A. | 登録日 | 2022-01-16 | 公開日 | 2022-09-14 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus. Cell Rep, 40, 2022
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7OXA
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![BU of 7oxa by Molmil](/molmil-images/mine/7oxa) | Target-bound SpCas9 complex with AAVS1 chimeric RNA-DNA guide | 分子名称: | AAVS1 non-target DNA strand, AAVS1 target DNA strand, CRISPR-associated endonuclease Cas9/Csn1, ... | 著者 | Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P. | 登録日 | 2021-06-22 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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7WZ6
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![BU of 7wz6 by Molmil](/molmil-images/mine/7wz6) | Crystal structure of MyoD-E47 | 分子名称: | Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1 | 著者 | Zhong, J, Huang, Y, Ma, J. | 登録日 | 2022-02-17 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis of the bHLH domains of MyoD-E47 heterodimer. Biochem.Biophys.Res.Commun., 621, 2022
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7X77
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![BU of 7x77 by Molmil](/molmil-images/mine/7x77) | Ectodomain structure of per os infectivity factor 5 | 分子名称: | Per os infectivity factor 5 | 著者 | Cao, S, Li, Z, Fu, Y. | 登録日 | 2022-03-09 | 公開日 | 2022-06-22 | 最終更新日 | 2022-08-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Characterization of Per Os Infectivity Factor 5 (PIF5) Reveals the Essential Role of Intramolecular Interactions in Baculoviral Oral Infectivity. J.Virol., 96, 2022
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8ODT
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![BU of 8odt by Molmil](/molmil-images/mine/8odt) | |
7XI7
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![BU of 7xi7 by Molmil](/molmil-images/mine/7xi7) | Human dihydrofolate reductase complexed with P39 | 分子名称: | 6-hexyl-5-phenyl-pyrimidine-2,4-diamine, Dihydrofolate reductase, SULFATE ION | 著者 | Vanichtanankul, J, Saeyang, T, Kamchonwongpaisan, S, Yuvaniyama, J, Yuthavong, Y. | 登録日 | 2022-04-12 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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7BTF
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![BU of 7btf by Molmil](/molmil-images/mine/7btf) | SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-04-01 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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7F5K
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![BU of 7f5k by Molmil](/molmil-images/mine/7f5k) | Crystal structure of TCR4-1 ectodomain | 分子名称: | T cell receptor alpha chain, T cell receptor beta chain | 著者 | Nagae, M, Yamasaki, S. | 登録日 | 2021-06-22 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.0000298 Å) | 主引用文献 | Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b. Nat Commun, 13, 2022
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7F6D
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![BU of 7f6d by Molmil](/molmil-images/mine/7f6d) | Reconstruction of the HerA-NurA complex from Deinococcus radiodurans | 分子名称: | HerA, NurA | 著者 | Xu, Y, Xu, L, Guo, J, Hua, Y, Zhao, Y. | 登録日 | 2021-06-25 | 公開日 | 2022-06-29 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Mechanisms of helicase activated DNA end resection in bacteria. Structure, 30, 2022
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7FGX
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![BU of 7fgx by Molmil](/molmil-images/mine/7fgx) | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P39, NADPH and dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6-hexyl-5-phenyl-pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, J, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | 登録日 | 2021-07-28 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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7OX7
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![BU of 7ox7 by Molmil](/molmil-images/mine/7ox7) | Target-bound SpCas9 complex with TRAC chimeric RNA-DNA guide | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P. | 登録日 | 2021-06-22 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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7FGY
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![BU of 7fgy by Molmil](/molmil-images/mine/7fgy) | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P40, NADPH and dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(3-chlorophenyl)-6-[2-(3-phenoxypropoxy)ethyl]pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, J, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | 登録日 | 2021-07-28 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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7T2S
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![BU of 7t2s by Molmil](/molmil-images/mine/7t2s) | Structure of E. coli upec-117 Cap18 3'-5' exonuclease | 分子名称: | 3'-5' exonuclease, ACETATE ION | 著者 | Liang, Q, Richey, S.T, Ye, Q, Lau, R.K, Corbett, K.D. | 登録日 | 2021-12-06 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structure and activity of a bacterial defense-associated 3'-5' exonuclease. Protein Sci., 31, 2022
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7OX9
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![BU of 7ox9 by Molmil](/molmil-images/mine/7ox9) | Target-bound SpCas9 complex with AAVS1 all-RNA guide | 分子名称: | AAVS1 non-target DNA strand, AAVS1 target DNA strand, CRISPR-associated endonuclease Cas9/Csn1, ... | 著者 | Pacesa, M, Donohoue, P, May, A.P, Jinek, M, Cameron, P. | 登録日 | 2021-06-22 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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3BRG
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![BU of 3brg by Molmil](/molmil-images/mine/3brg) | CSL (RBP-Jk) bound to DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), ... | 著者 | Friedmann, D.R, Kovall, R.A. | 登録日 | 2007-12-21 | 公開日 | 2008-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex. J.Biol.Chem., 283, 2008
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7FGW
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![BU of 7fgw by Molmil](/molmil-images/mine/7fgw) | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with pyrimethamine, NADPH and dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, BENZAMIDINE, ... | 著者 | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, Y, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | 登録日 | 2021-07-28 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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7OKW
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![BU of 7okw by Molmil](/molmil-images/mine/7okw) | 1.62A X-ray crystal structure of the conserved C-terminal (CCT) of human OSR1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Bax, B.D, Elvers, K.T, Lipka-Lloyd, M, Mehellou, Y. | 登録日 | 2021-05-18 | 公開日 | 2021-09-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains. Chembiochem, 23, 2022
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7SXQ
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![BU of 7sxq by Molmil](/molmil-images/mine/7sxq) | Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | 分子名称: | 1,2-ETHANEDIOL, Apicoplast DNA polymerase, CHLORIDE ION, ... | 著者 | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | 登録日 | 2021-11-24 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243, 2022
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6T4Q
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![BU of 6t4q by Molmil](/molmil-images/mine/6t4q) | Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination. | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | 登録日 | 2019-10-14 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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