CSL (RBP-Jk) bound to DNA

Summary for 3BRG

Related3BRD 3BRF
DescriptorDNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), Recombining binding protein suppressor of hairless, ... (5 entities in total)
Functional Keywordsprotein-dna complex, signaling, transcription, notch, activator, alternative splicing, dna-binding, notch signaling pathway, nucleus, repressor, transcription regulation, dna binding protein-dna complex, dna binding protein/dna
Biological sourceMus musculus (house mouse)
Cellular locationNucleus P31266
Total number of polymer chains3
Total molecular weight58202.91
Friedmann, D.R.,Kovall, R.A. (deposition date: 2007-12-21, release date: 2008-04-01, Last modification date: 2017-10-25)
Primary citation
Friedmann, D.R.,Wilson, J.J.,Kovall, R.A.
RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
J.Biol.Chem., 283:14781-14791, 2008
PubMed: 18381292 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M709501200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27010 1.5% 9.3% 13.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14