7SXQ
Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag
Summary for 7SXQ
| Entry DOI | 10.2210/pdb7sxq/pdb |
| Related | 5DKU |
| Descriptor | Apicoplast DNA polymerase, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | dna polymerase, exonulease, apicoplast, plasmodium falciparum, replication, transferase |
| Biological source | Plasmodium falciparum (isolate 3D7) |
| Total number of polymer chains | 2 |
| Total formula weight | 148672.95 |
| Authors | Nieto, N.,Chheda, P.,Kerns, R.,Nelson, S.,Honzatko, R. (deposition date: 2021-11-24, release date: 2022-10-19, Last modification date: 2023-10-18) |
| Primary citation | Chheda, P.R.,Nieto, N.,Kaur, S.,Beck, J.M.,Beck, J.R.,Honzatko, R.,Kerns, R.J.,Nelson, S.W. Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243:114751-114751, 2022 Cited by PubMed: 36191407DOI: 10.1016/j.ejmech.2022.114751 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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