8Z8N
 
 | | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 3 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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9BJU
 | | Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 | | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, ACETATE ION, ... | | 著者 | Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. | | 登録日 | 2024-04-25 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability
To Be Published
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8XAY
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8XP8
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3LWW
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8X8N
 | | Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha, ... | | 著者 | Xu, H.E, You, C, Zhao, L, Li, J. | | 登録日 | 2023-11-27 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex
To Be Published
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8Z97
 | | Cryo-EM structure of Thogoto virus polymerase in a transcription elongation conformation | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8YGJ
 | | SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt) | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | | 登録日 | 2024-02-26 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
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3LXK
 | | Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 | | 分子名称: | 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase JAK3 | | 著者 | Chrencik, J.E, Patny, A, Leung, I.K, Korniski, B, Emmons, T.L, Benson, T.E. | | 登録日 | 2010-02-25 | | 公開日 | 2010-06-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6.
J.Mol.Biol., 400, 2010
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8XOB
 | | VMAT2 protonated state | | 分子名称: | Synaptic vesicular amine transporter,transporter B | | 著者 | Jiang, D.H, Wu, D. | | 登録日 | 2023-12-31 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | VMAT2 protonated state
To Be Published
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8YX1
 | | CD40 in complex with Bleselumab Fab | | 分子名称: | Bleselumab, heavy chain, light chain, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2024-04-01 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
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3LL3
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8XF0
 | | Crystal structure of the dissociated C-phycocyanin alpha-chain from Thermoleptolyngbya sp. O-77 | | 分子名称: | C-phycocyanin alpha chain, MAGNESIUM ION, PHYCOCYANOBILIN | | 著者 | Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S. | | 登録日 | 2023-12-13 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
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9B5X
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6DHS
 | | Structure of hnRNP H qRRM1,2 | | 分子名称: | Heterogeneous nuclear ribonucleoprotein H | | 著者 | Meagher, J.L, Stuckey, J.A. | | 登録日 | 2018-05-21 | | 公開日 | 2018-09-12 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
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8YUV
 | | Cryo-EM structure of the immepip-bound H3R-Gi complex | | 分子名称: | 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | 登録日 | 2024-03-27 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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8Z8J
 | | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 2 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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6QL6
 | | Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom | | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ... | | 著者 | Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A. | | 登録日 | 2019-01-31 | | 公開日 | 2020-03-18 | | 最終更新日 | 2020-04-08 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
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8Z85
 | | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 1 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | | 登録日 | 2024-04-21 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8YR3
 | | Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH | | 分子名称: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE | | 著者 | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | | 登録日 | 2024-03-20 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of cadmium-bound human ABCB6.
Commun Biol, 7, 2024
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8YKW
 | | Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | | 登録日 | 2024-03-05 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1.
Cell Res., 34, 2024
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3LP8
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8ZMS
 | | Acetylcholine-bound VAChT | | 分子名称: | ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 | | 著者 | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | | 登録日 | 2024-05-23 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insights into VAChT neurotransmitter recognition and inhibition.
Cell Res., 2024
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3LNC
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9BFL
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