PDB: 437 件ウェブページステータス検索Chemie searchBIRD

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8PI4	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI6	Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI5	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ... 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PJH	Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
6U46	Solution Structure of a Heat-Resistant Long-Acting Insulin Analog 分子名称: Insulin 著者 Yang, Y, Weiss, M.A. 登録日 2019-08-23 公開日 2020-08-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution Structure of a Heat-Resistant Long-Acting Insulin Analog To Be Published
1QJ0	HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. 登録日 1999-06-18 公開日 1999-06-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
1QIY	HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH PHENOL 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. 登録日 1999-06-18 公開日 1999-06-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
1RWE	Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z, Xu, B, Chu, Y.C, Li, B, Nakagawa, S.H, Qu, Y, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A. 登録日 2003-12-16 公開日 2005-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. Biochemistry, 43, 2004
3GF1	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY 分子名称: INSULIN-LIKE GROWTH FACTOR I 著者 Cooke, R.M, Harvey, T.S, Campbell, I.D. 登録日 1991-01-24 公開日 1993-04-15 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry, 30, 1991
4IYD	Insulin glargine crystal structure 1 分子名称: Insulin A chain, Insulin B chain 著者 Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A. 登録日 2013-01-28 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference to be published
3GKY	The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. 登録日 2009-03-11 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY. J.Biol.Chem., 284, 2009
4IUZ	High resolution crystal structure of racemic ester insulin 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... 著者 Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. 登録日 2013-01-22 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
4IYF	Insulin glargine crystal structure 2 分子名称: Insulin A chain, Insulin B chain 著者 Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A. 登録日 2013-01-28 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference to be published
2BN1	Insulin after a high dose x-ray burn 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-18 公開日 2005-09-07 最終更新日 2013-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
6INS	X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE 分子名称: INSULIN, ZINC ION 著者 Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. 登録日 1992-11-25 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
2BN3	Insulin before a high dose x-ray burn 分子名称: INSULIN 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-18 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
6JR3	Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body 分子名称: Insulin A chain, Insulin B chain 著者 Sengupta, J, Pathak, B.K, Bhakta, S. 登録日 2019-04-02 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (14.5 Å) 主引用文献 Resveratrol as a nontoxic excipient stabilizes insulin in a bioactive hexameric form. J.Comput.Aided Mol.Des., 34, 2020
2C8R	insuline(60sec) and UV laser excited fluorescence 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. 登録日 2005-12-06 公開日 2006-03-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
2C8Q	insuline(1sec) and UV laser excited fluorescence 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. 登録日 2005-12-06 公開日 2006-03-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
3INC	Crystal structure of human insulin with Ni+2 complex 分子名称: Insulin A chain, Insulin B chain, NICKEL (II) ION 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-12 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
3INS	STRUCTURE OF INSULIN. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT 分子名称: INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION 著者 Wlodawer, A, Savage, H. 登録日 1988-10-14 公開日 1989-01-09 最終更新日 2017-11-29 実験手法 NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION 主引用文献 Structure of insulin: results of joint neutron and X-ray refinement. Acta Crystallogr.,Sect.B, 45, 1989
3IR0	Crystal Structure of Human Insulin complexed with Cu+2 metal ion 分子名称: COPPER (II) ION, Insulin A chain, Insulin B chain 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-21 公開日 2010-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Metal induced structural changes observed in Human insulin To be Published
3ILG	Crystal structure of humnan insulin Sr+2 complex 分子名称: Insulin A chain, Insulin B chain, STRONTIUM ION 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-07 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
2EFA	Neutron crystal structure of cubic insulin at pD6.6 分子名称: Insulin 著者 Ishikawa, T, Tanaka, I, Niimura, N. 登録日 2007-02-22 公開日 2008-01-22 最終更新日 2023-10-25 実験手法 NEUTRON DIFFRACTION (2.7 Å) 主引用文献 A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6 Chem.Phys., 345, 2008
6K59	Structure of Glargine insulin in 20% acetic acid-d4 (pH 1.9) 分子名称: Glargine Insulin Chain-A, Glargine insulin Chain-B 著者 Ratha, B.N, Kar, R.K, Bhunia, A. 登録日 2019-05-28 公開日 2020-05-06 実験手法 SOLUTION NMR 主引用文献 Molecular Details of a Salt Bridge and Its Role in Insulin Fibrillation by NMR and Raman Spectroscopic Analysis. J.Phys.Chem.B, 124, 2020

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