8SVK
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![BU of 8svk by Molmil](/molmil-images/mine/8svk) | Crystal structure of Bax D71N core domain BH3-groove dimer | 分子名称: | Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Miller, M.S, Czabotar, P.E, Colman, P.M. | 登録日 | 2023-05-16 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SF5
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8SPF
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![BU of 8spf by Molmil](/molmil-images/mine/8spf) | Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with 2-stearoyl lysoPC | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, DODECANE, ... | 著者 | Cowan, A.D, Miller, M.S, Czabotar, P.E, Colman, P.M. | 登録日 | 2023-05-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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7C3D
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![BU of 7c3d by Molmil](/molmil-images/mine/7c3d) | Crystal structure of AofleA from Arthrobotrys oligospora in complex with D-arabinose | 分子名称: | AofleA, GLYCEROL, alpha-D-arabinopyranose, ... | 著者 | Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M. | 登録日 | 2020-05-12 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.596 Å) | 主引用文献 | Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora. Int.J.Biol.Macromol., 164, 2020
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8SRX
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![BU of 8srx by Molmil](/molmil-images/mine/8srx) | Crystal structure of BAK-BAX heterodimer with lysoPC | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, Bcl-2 homologous antagonist/killer, ... | 著者 | Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S. | 登録日 | 2023-05-07 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SWI
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5W85
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8SXX
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![BU of 8sxx by Molmil](/molmil-images/mine/8sxx) | E. coli dodecamer SIR2 | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
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8SRY
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![BU of 8sry by Molmil](/molmil-images/mine/8sry) | Crystal structure of BAK-BAX heterodimer with C12E8 | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, ... | 著者 | Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S. | 登録日 | 2023-05-08 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SUB
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![BU of 8sub by Molmil](/molmil-images/mine/8sub) | E. coli SIR2-HerA complex (dodecamer SIR2 pentamer HerA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ... | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | 登録日 | 2023-05-11 | 公開日 | 2023-12-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
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8SPE
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![BU of 8spe by Molmil](/molmil-images/mine/8spe) | Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P31 | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, ... | 著者 | Miller, M.S, Cowan, A.D, Colman, P.M, Czabotar, P.E. | 登録日 | 2023-05-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SGE
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![BU of 8sge by Molmil](/molmil-images/mine/8sge) | KLHDC2 Kelch Domain with ligand KDRLKZ-1 | 分子名称: | GLYCEROL, Kelch domain-containing protein 2, [(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic acid | 著者 | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | 登録日 | 2023-04-12 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.509 Å) | 主引用文献 | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8SH2
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![BU of 8sh2 by Molmil](/molmil-images/mine/8sh2) | KLHDC2 in complex with EloB and EloC | 分子名称: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | 著者 | Digianantonio, K.M, Bekes, M. | 登録日 | 2023-04-13 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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7CJF
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![BU of 7cjf by Molmil](/molmil-images/mine/7cjf) | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | 著者 | Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. | 登録日 | 2020-07-10 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | 主引用文献 | A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun, 12, 2021
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8SMC
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![BU of 8smc by Molmil](/molmil-images/mine/8smc) | Cryo-EM structure of LRRK2 bound with type-I inhibitor DNL201 | 分子名称: | 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile, GUANOSINE-5'-DIPHOSPHATE, non-specific serine/threonine protein kinase | 著者 | Sun, J, Zhu, H. | 登録日 | 2023-04-26 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | 主引用文献 | Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382, 2023
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8SQG
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![BU of 8sqg by Molmil](/molmil-images/mine/8sqg) | OXA-48 bound to inhibitor CDD-2801 | 分子名称: | (1M)-3'-(benzyloxy)-5-[2-(methylamino)-2-oxoethoxy][1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | 著者 | Park, S, Judge, A, Fan, J, Sankaran, B, Palzkill, T. | 登録日 | 2023-05-04 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
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8SQF
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![BU of 8sqf by Molmil](/molmil-images/mine/8sqf) | OXA-48 bound to inhibitor CDD-2725 | 分子名称: | (1M)-3'-(benzyloxy)-5-hydroxy[1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | 著者 | Park, S, Judge, A, Fan, J, Sankaran, B, Prasad, B.V.V, Palzkill, T. | 登録日 | 2023-05-04 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
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8T12
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8SVC
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![BU of 8svc by Molmil](/molmil-images/mine/8svc) | Crystal Structure of SBP from Klebsiella pneumoniae | 分子名称: | Metal ABC transporter substrate-binding protein, SULFATE ION, ZINC ION | 著者 | Giles, M.W, Cole, G.B, Ng, D, McDevitt, C.A, Moraes, T.F. | 登録日 | 2023-05-16 | 公開日 | 2024-01-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Zinc acquisition and its contribution to Klebsiella pneumoniae virulence. Front Cell Infect Microbiol, 13, 2023
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8SX9
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8SXQ
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5WF1
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8T13
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2LVZ
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![BU of 2lvz by Molmil](/molmil-images/mine/2lvz) | Solution structure of a Eosinophil Cationic Protein-trisaccharide heparin mimetic complex | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-propan-2-yl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Eosinophil cationic protein | 著者 | Garcia Mayoral, M, Canales, A, Diaz, D, Lopez Prados, J, Moussaoui, M, de Paz, J, Angulo, J, Nieto, P, Jimenez Barbero, J, Boix, E, Bruix, M. | 登録日 | 2012-07-17 | 公開日 | 2013-07-31 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Insights into the glycosaminoglycan-mediated cytotoxic mechanism of eosinophil cationic protein revealed by NMR. Acs Chem.Biol., 8, 2013
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8SX8
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