8SXX

E. coli dodecamer SIR2

Summary for 8SXX

Entry DOI	10.2210/pdb8sxx/pdb
EMDB information	40860
Descriptor	SIR2-like domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total)
Functional Keywords	sir2, nadase, nuclease, anti-phage system, immune system
Biological source	Escherichia coli
Total number of polymer chains	12
Total formula weight	569773.07
Authors	Shen, Z.F.,Lin, Q.P.,Fu, T.M. (deposition date: 2023-05-24, release date: 2023-12-27, Last modification date: 2024-03-27)
Primary citation	Shen, Z.,Lin, Q.,Yang, X.Y.,Fosuah, E.,Fu, T.M. Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83:4586-4599.e5, 2023 Cited by PubMed: 38096827 DOI: 10.1016/j.molcel.2023.11.007 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation