8SVK
Crystal structure of Bax D71N core domain BH3-groove dimer
Summary for 8SVK
Entry DOI | 10.2210/pdb8svk/pdb |
Related | 8G1T 8SPE 8SPF 8SPZ 8SRX 8SRY |
Descriptor | Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | bax, bcl2, apoptosis |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 36944.14 |
Authors | Miller, M.S.,Czabotar, P.E.,Colman, P.M. (deposition date: 2023-05-16, release date: 2023-12-27, Last modification date: 2024-06-19) |
Primary citation | Miller, M.S.,Cowan, A.D.,Brouwer, J.M.,Smyth, S.T.,Peng, L.,Wardak, A.Z.,Uren, R.T.,Luo, C.,Roy, M.J.,Shah, S.,Tan, Z.,Reid, G.E.,Colman, P.M.,Czabotar, P.E. Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291:2335-2353, 2024 Cited by PubMed: 38088212DOI: 10.1111/febs.17031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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