8SVK

Crystal structure of Bax D71N core domain BH3-groove dimer

Summary for 8SVK

• Entry DOI: 10.2210/pdb8svk/pdb
• Related: 8G1T 8SPE 8SPF 8SPZ 8SRX 8SRY
• Descriptor: Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... (6 entities in total)
• Functional Keywords: bax, bcl2, apoptosis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 36944.14

Authors

Miller, M.S.,Czabotar, P.E.,Colman, P.M. (deposition date: 2023-05-16, release date: 2023-12-27)

• Primary citation: Miller, M.S.,Cowan, A.D.,Brouwer, J.M.,Smyth, S.T.,Peng, L.,Wardak, A.Z.,Uren, R.T.,Luo, C.,Roy, M.J.,Shah, S.,Tan, Z.,Reid, G.E.,Colman, P.M.,Czabotar, P.E.; Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.; Febs J., 2023; PubMed: 38088212; DOI: 10.1111/febs.17031

Experimental method

X-RAY DIFFRACTION (2.25 Å)