8SVK
Crystal structure of Bax D71N core domain BH3-groove dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Apoptosis regulator BAX | polymer | 81 | 8971.2 | 4 | UniProt (Q07812) Pfam (PF00452) | Homo sapiens (human) | Bcl-2-like protein 4,Bcl2-L-4 |
| 2 | E, H, K (A, B, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 3 | F, G, I (A, B, D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 4 | J (D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | L (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | M, N, O (A, B, D) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 53 - 128 (UniProt: Q07812)
| PDB | External Database | Details |
|---|---|---|
| Gly 48 | - | expression tag |
| Pro 49 | - | expression tag |
| Leu 50 | - | expression tag |
| Gly 51 | - | expression tag |
| Ser 52 | - | expression tag |
| Ser 62 | Cys 62 | engineered mutation |
| Asn 71 | Asp 71 | engineered mutation |
| Ser 126 | Cys 126 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35885.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1059.2 | |
| All* | Total formula weight | 36944.1 |
