8SX8
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc
Summary for 8SX8
| Entry DOI | 10.2210/pdb8sx8/pdb |
| EMDB information | 40827 |
| Descriptor | Multidrug resistance-associated protein 4, 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid (3 entities in total) |
| Functional Keywords | abc transporter, multidrug resistance-associated protein, membrane protein, transport protein |
| Biological source | Bos taurus (cattle) |
| Total number of polymer chains | 1 |
| Total formula weight | 149941.78 |
| Authors | Pourmal, S.,Stroud, R.M. (deposition date: 2023-05-20, release date: 2024-01-17, Last modification date: 2024-03-13) |
| Primary citation | Pourmal, S.,Green, E.,Bajaj, R.,Chemmama, I.E.,Knudsen, G.M.,Gupta, M.,Sali, A.,Cheng, Y.,Craik, C.S.,Kroetz, D.L.,Stroud, R.M. Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38216659DOI: 10.1038/s41594-023-01176-4 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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