7P49
 
 | | HLA-E*01:03 in complex with Mtb14 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Walters, L.C, Gillespie, G.M. | | 登録日 | 2021-07-10 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
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7PB2
 | | Crystal structure of JDI TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK) | | 分子名称: | Beta-2-microglobulin, KRAS G12D peptide (VVVGADGVGK), MHC class I antigen, ... | | 著者 | Coles, C.H, Karuppiah, V, Robinson, R.A. | | 登録日 | 2021-07-30 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Nat Commun, 13, 2022
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7OW5
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7OW6
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7OW3
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7OW4
 | | Crystal structure of HLA-A*11:01 in complex with KRAS G12D peptide (VVVGADGVGK) | | 分子名称: | Beta-2-microglobulin, KRAS G12D peptide (VVVGADGVGK), MHC class I antigen, ... | | 著者 | Coles, C.H, Karuppiah, V, Robinson, R.A. | | 登録日 | 2021-06-16 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Nat Commun, 13, 2022
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7P4B
 | | HLA-E*01:03 in complex with IL9 | | 分子名称: | Beta-2-microglobulin, ESAT-6-like protein EsxH, GLYCEROL, ... | | 著者 | Walters, L.C, Gillespie, G.M. | | 登録日 | 2021-07-10 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
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7PBC
 | | Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | 著者 | Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. | | 登録日 | 2021-08-02 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
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7PDY
 | | A viral peptide from Marek's disease virus bound to chicken MHC-II molecule | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 38 kDa phosphoprotein,MHC class II beta chain, ... | | 著者 | Goryanin, A, Cook, A.G, Kaufman, J, Halabi, S. | | 登録日 | 2021-08-09 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Viral peptide bound to chicken MHC-II molecule
To Be Published
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7PHR
 | | Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Susac, L, Thomas, C, Tampe, R. | | 登録日 | 2021-08-18 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.
Cell, 185, 2022
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7Q15
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7PDW
 | | Crystal structure of parent TCR (728) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | | 著者 | Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. | | 登録日 | 2021-08-09 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
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7QNG
 | | Structure of a MHC I-Tapasin-ERp57 complex | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R. | | 登録日 | 2021-12-20 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
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7QPD
 | | Structure of the human MHC I peptide-loading complex editing module | | 分子名称: | Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ... | | 著者 | Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R. | | 登録日 | 2022-01-03 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Molecular basis of MHC I quality control in the peptide loading complex.
Nat Commun, 13, 2022
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7QHP
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7QPJ
 | | Crystal structure of engineered TCR (756) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | | 著者 | Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. | | 登録日 | 2022-01-04 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
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6X00
 | | Structure of DbNA(11) peptides bound to H-2Db MHC-I | | 分子名称: | Beta-2-microglobulin, Epitope from Neuraminidase Protein (NA-181-191), H-2 class I histocompatibility antigen, ... | | 著者 | Farenc, C, Rossjohn, J. | | 登録日 | 2020-05-14 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Overlapping Peptides Elicit Distinct CD8 + T Cell Responses following Influenza A Virus Infection.
J Immunol., 205, 2020
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6WZY
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8GZN
 | | IgM-var2CSA complex | | 分子名称: | Erythrocyte membrane protein 1, Immunoglobulin J chain, Immunoglobulin heavy constant mu | | 著者 | Akhouri, R.R, Goel, S, Skoglund, U. | | 登録日 | 2022-09-27 | | 公開日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-electron microscopy of IgM-VAR2CSA complex reveals IgM inhibits binding of Plasmodium falciparum to Chondroitin Sulfate A.
Nat Commun, 14, 2023
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6WNA
 | | Next generation monomeric IgG4 Fc | | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... | | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | | 登録日 | 2020-04-22 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
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6WOL
 | | Next generation monomeric IgG4 Fc bound to neonatal Fc receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... | | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | | 登録日 | 2020-04-24 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
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6XQA
 | | Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus | | 分子名称: | Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... | | 著者 | Nguyen, A.T, Szeto, C, Gras, S. | | 登録日 | 2020-07-09 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Nat Commun, 12, 2021
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6XCO
 | | Immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, GLYCEROL, ... | | 著者 | Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Jones, M.C, Tresoldi, E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H. | | 登録日 | 2020-06-08 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
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6XC9
 | | Immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Tresoldi, M.C.E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H. | | 登録日 | 2020-06-08 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
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6XCP
 | | Immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hybrid insulin peptide, ... | | 著者 | Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Jones, M.C, Tresoldi, E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H. | | 登録日 | 2020-06-08 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
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