7QPD

Structure of the human MHC I peptide-loading complex editing module

Summary for 7QPD

• Entry DOI: 10.2210/pdb7qpd/pdb
• Related: 6ENY
• EMDB information: 14119
• Descriptor: Beta-2-microglobulin, Tapasin, Protein disulfide-isomerase A3, ... (7 entities in total)
• Functional Keywords: antigen processing, peptide proofreading, chaperones, mhc i, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 198558.84

Authors

Domnick, A.,Susac, L.,Trowitzsch, S.,Thomas, C.,Tampe, R. (deposition date: 2022-01-03, release date: 2022-07-20, Last modification date: 2022-08-24)

• Primary citation: Domnick, A.,Winter, C.,Susac, L.,Hennecke, L.,Hensen, M.,Zitzmann, N.,Trowitzsch, S.,Thomas, C.,Tampe, R.; Molecular basis of MHC I quality control in the peptide loading complex.; Nat Commun, 13:4701-4701, 2022; PubMed: 35948544; DOI: 10.1038/s41467-022-32384-z

Experimental method

ELECTRON MICROSCOPY (3.73 Å)