6XCP

Immune receptor complex

Summary for 6XCP

• Entry DOI: 10.2210/pdb6xcp/pdb
• Descriptor: MHC class II HLA-DQ-alpha chain, Hybrid insulin peptide, MHC class II HLA-DQ8-beta chain fusion, T-CELL-RECEPTOR, A2.13-alpha chain, ... (8 entities in total)
• Functional Keywords: complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 98470.21

Authors

Tran, T.M.,Faridi, P.,Lim, J.J.,Ting, T.Y.,Onwukwe, G.,Bhattacharjee, P.,Jones, M.C.,Tresoldi, E.,Cameron, J.F.,La-Gruta, L.N.,Purcell, W.A.,Mannering, I.S.,Rossjohn, J.,Reid, H.H. (deposition date: 2020-06-08, release date: 2021-07-14, Last modification date: 2023-10-18)

• Primary citation: Tran, M.T.,Faridi, P.,Lim, J.J.,Ting, Y.T.,Onwukwe, G.,Bhattacharjee, P.,Jones, C.M.,Tresoldi, E.,Cameron, F.J.,La Gruta, N.L.,Purcell, A.W.,Mannering, S.I.,Rossjohn, J.,Reid, H.H.; T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.; Nat Commun, 12:5110-5110, 2021; PubMed: 34433824; DOI: 10.1038/s41467-021-25404-x

Experimental method

X-RAY DIFFRACTION (3.3 Å)