6XCP

Immune receptor complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MHC class II HLA-DQ-alpha chain	polymer	193	21929.3	1	UniProt (Q30069) Pfam (PF00993) Pfam (PF07654)	Homo sapiens (Human)
2	B (C)	Hybrid insulin peptide, MHC class II HLA-DQ8-beta chain fusion	polymer	230	26071.0	1	UniProt (O19707) Pfam (PF00969) Pfam (PF07654)	Homo sapiens (Human)	HIP
3	C (D)	T-CELL-RECEPTOR, A2.13-alpha chain	polymer	203	22633.2	1		Homo sapiens (Human)
4	D (E)	T-CELL-RECEPTOR, A2.13-beta chain	polymer	240	27207.3	1		Homo sapiens (Human)
5	E, G (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	F (C)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	H (D)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
8	I, J, K, L (A, C, D, E)	water	water		18.0	35	Chemie (HOH)

Sequence modifications

A: -1 - 181 (UniProt: Q30069)

PDB	External Database	Details
Cys 72	Ile 75	engineered mutation
Ser 182	-	expression tag
Thr 183	-	expression tag
Gly 184	-	expression tag
Gly 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Asp 189	-	expression tag
Lys 190	-	expression tag

C: -2 - 12 (PDB: 6XCP)

PDB	External Database	Details
Gly 13	-	linker
Ser 14	-	linker
Gly 15	-	linker
Gly 16	-	linker
Ser 17	-	linker
Ile 18	-	linker
Glu 19	-	linker
Gly 20	-	linker
Arg 21	-	linker
Gly 22	-	linker
Gly 23	-	linker
Ser 24	-	linker
Gly 25	-	linker
Ala 26	-	linker
Ser 27	-	linker

C: 28 - 219 (UniProt: O19707)

PDB	External Database	Details
Thr 220	-	expression tag
Gly 221	-	expression tag
Gly 222	-	expression tag
Asp 223	-	expression tag
Asp 224	-	expression tag
Asp 225	-	expression tag
Asp 226	-	expression tag
Lys 227	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97840.7
Non-Polymers*	Number of molecules	4
	Total formula weight	629.5
All*	Total formula weight	98470.2

*Water molecules are not included.