7PDW
Crystal structure of parent TCR (728) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide
This is a non-PDB format compatible entry.
Summary for 7PDW
Entry DOI | 10.2210/pdb7pdw/pdb |
Related | 7PBC |
Descriptor | T-cell receptor alpha chain (TRAV/TRAC), T-cell receptor beta chain (TRBV/TRBC), Beta-2-microglobulin, ... (8 entities in total) |
Functional Keywords | t-cell receptor, human leukocyte antigen, mage-a10, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 190280.19 |
Authors | Simister, P.C.,Border, E.C.,Vieira, J.F.,Pumphrey, N.J. (deposition date: 2021-08-09, release date: 2022-08-03, Last modification date: 2024-01-31) |
Primary citation | Simister, P.C.,Border, E.C.,Vieira, J.F.,Pumphrey, N.J. Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10:-, 2022 Cited by PubMed: 35851311DOI: 10.1136/jitc-2022-004600 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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