5JCS
| CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E. | 登録日 | 2016-04-15 | 公開日 | 2016-11-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling Nat.Struct.Mol.Biol., 23, 2016
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6HHQ
| Crystal structure of compound C45 bound to the yeast 80S ribosome | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | 登録日 | 2018-08-28 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.10000038 Å) | 主引用文献 | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
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5IT9
| Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES. | 分子名称: | 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ... | 著者 | Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. | 登録日 | 2016-03-16 | 公開日 | 2016-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
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6HCQ
| Structure of the rabbit collided di-ribosome (collided monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-16 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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5IT7
| Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2 | 分子名称: | (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. | 登録日 | 2016-03-16 | 公開日 | 2016-05-18 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
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5K0Y
| m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-17 | 公開日 | 2016-07-13 | 最終更新日 | 2018-04-18 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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5L8W
| Structure of USP12-UB-PRG/UAF1 | 分子名称: | GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ... | 著者 | Dharadhar, S, Sixma, T. | 登録日 | 2016-06-08 | 公開日 | 2016-09-28 | 最終更新日 | 2016-11-30 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
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6J6H
| Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | 分子名称: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6Q
| Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6N
| Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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5T2A
| CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution | 分子名称: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Zhang, X, Lai, M, Zhou, Z.H. | 登録日 | 2016-08-23 | 公開日 | 2017-01-25 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
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5UKM
| bovine GRK2 in complex with human Gbetagamma subunits and CCG258208 (14as) | 分子名称: | 5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(1H-pyrazol-5-yl)methyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Cruz-Rodriguez, O, Tesmer, J.J.G. | 登録日 | 2017-01-23 | 公開日 | 2017-04-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J. Med. Chem., 60, 2017
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5UKK
| Human GRK2 in complex with human G-beta-gamma subunits and CCG211998 (14ak) | 分子名称: | 5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(pyridin-2-yl)methyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Cato, M.C, Homan, K.T, Tesmer, J.J.G. | 登録日 | 2017-01-23 | 公開日 | 2017-04-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J. Med. Chem., 60, 2017
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5UZ7
| Volta phase plate cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | 分子名称: | Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liang, Y.L, Khoshouei, M, Radjainia, M, Zhang, Y, Glukhova, A, Tarrasch, J, Thal, D.M, Furness, S.G.B, Christopoulos, G, Coudrat, T, Danev, R, Baumeister, W, Miller, L.J, Christopoulos, A, Kobilka, B.K, Wootten, D, Skiniotis, G, Sexton, P.M. | 登録日 | 2017-02-24 | 公開日 | 2017-05-03 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Nature, 546, 2017
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5TGA
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5TBW
| Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D. | 登録日 | 2016-09-13 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nat Chem, 9, 2017
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5VAI
| Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein | 分子名称: | Glucagon-like peptide 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, Y, Sun, B, Feng, D, Hu, H, Chu, M, Qu, Q, Tarrasch, J.T, Li, S, Kobilka, T.S, Kobilka, B.K, Skiniotis, G. | 登録日 | 2017-03-27 | 公開日 | 2017-05-24 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature, 546, 2017
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5UKL
| Human GRK2 in complex with Gbetagamma subunits and CCG222886 (14bd) | 分子名称: | 2-{5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluorophenyl}-N-[2-(1H-pyrazol-4-yl)ethyl]acetamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Cato, M.C, Homan, K.T, Tesmer, J.J.G. | 登録日 | 2017-01-23 | 公開日 | 2017-04-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J. Med. Chem., 60, 2017
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5TGM
| Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | 著者 | Melnikov, S, Mailliot, J, Yusupov, M. | 登録日 | 2016-09-28 | 公開日 | 2017-01-18 | 最終更新日 | 2022-12-07 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
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5T2C
| CryoEM structure of the human ribosome at 3.6 Angstrom resolution | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Zhang, X, Lai, M, Zhou, Z.H. | 登録日 | 2016-08-23 | 公開日 | 2017-01-25 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
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5TZS
| Architecture of the yeast small subunit processome | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 3' domain-associated, ... | 著者 | Chaker-Margot, M, Barandun, J, Hunziker, M, Klinge, S. | 登録日 | 2016-11-22 | 公開日 | 2016-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Architecture of the yeast small subunit processome. Science, 355, 2017
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5VYC
| Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A. | 登録日 | 2017-05-24 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Rep, 20, 2017
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3J6Y
| S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | 著者 | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | 登録日 | 2014-04-16 | 公開日 | 2014-06-11 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center. Proc.Natl.Acad.Sci.USA, 111, 2014
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3JAG
| Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | 登録日 | 2015-06-10 | 公開日 | 2015-08-12 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Structural basis for stop codon recognition in eukaryotes. Nature, 524, 2015
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3JCT
| Cryo-em structure of eukaryotic pre-60S ribosomal subunits | 分子名称: | 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | 著者 | Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N. | 登録日 | 2016-03-09 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes Nature, 534, 2016
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