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5JCS
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BU of 5jcs by Molmil
CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E.
登録日2016-04-15
公開日2016-11-16
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Nat.Struct.Mol.Biol., 23, 2016
6HHQ
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BU of 6hhq by Molmil
Crystal structure of compound C45 bound to the yeast 80S ribosome
分子名称: (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Pellegrino, S, Vanderwal, C.D, Yusupov, M.
登録日2018-08-28
公開日2019-02-20
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.10000038 Å)
主引用文献Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47, 2019
5IT9
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BU of 5it9 by Molmil
Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES.
分子名称: 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ...
著者Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S.
登録日2016-03-16
公開日2016-05-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
6HCQ
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BU of 6hcq by Molmil
Structure of the rabbit collided di-ribosome (collided monosome)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
登録日2018-08-16
公開日2018-10-17
最終更新日2018-11-14
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
5IT7
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BU of 5it7 by Molmil
Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2
分子名称: (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S.
登録日2016-03-16
公開日2016-05-18
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
5K0Y
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BU of 5k0y by Molmil
m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face
分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
著者Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y.
登録日2016-05-17
公開日2016-07-13
最終更新日2018-04-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
5L8W
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BU of 5l8w by Molmil
Structure of USP12-UB-PRG/UAF1
分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ...
著者Dharadhar, S, Sixma, T.
登録日2016-06-08
公開日2016-09-28
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
6J6H
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BU of 6j6h by Molmil
Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom
分子名称: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
登録日2019-01-15
公開日2019-04-24
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
6J6Q
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BU of 6j6q by Molmil
Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
登録日2019-01-15
公開日2019-04-24
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
6J6N
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BU of 6j6n by Molmil
Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
登録日2019-01-15
公開日2019-04-24
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
5T2A
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BU of 5t2a by Molmil
CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution
分子名称: 18S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Zhang, X, Lai, M, Zhou, Z.H.
登録日2016-08-23
公開日2017-01-25
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
5UKM
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BU of 5ukm by Molmil
bovine GRK2 in complex with human Gbetagamma subunits and CCG258208 (14as)
分子名称: 5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(1H-pyrazol-5-yl)methyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cruz-Rodriguez, O, Tesmer, J.J.G.
登録日2017-01-23
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.
J. Med. Chem., 60, 2017
5UKK
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BU of 5ukk by Molmil
Human GRK2 in complex with human G-beta-gamma subunits and CCG211998 (14ak)
分子名称: 5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(pyridin-2-yl)methyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cato, M.C, Homan, K.T, Tesmer, J.J.G.
登録日2017-01-23
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.
J. Med. Chem., 60, 2017
5UZ7
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BU of 5uz7 by Molmil
Volta phase plate cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex
分子名称: Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Liang, Y.L, Khoshouei, M, Radjainia, M, Zhang, Y, Glukhova, A, Tarrasch, J, Thal, D.M, Furness, S.G.B, Christopoulos, G, Coudrat, T, Danev, R, Baumeister, W, Miller, L.J, Christopoulos, A, Kobilka, B.K, Wootten, D, Skiniotis, G, Sexton, P.M.
登録日2017-02-24
公開日2017-05-03
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Nature, 546, 2017
5TGA
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BU of 5tga by Molmil
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Melnikov, S, Mailliot, J.
登録日2016-09-27
公開日2016-11-23
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5TBW
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BU of 5tbw by Molmil
Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D.
登録日2016-09-13
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
5VAI
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BU of 5vai by Molmil
Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein
分子名称: Glucagon-like peptide 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, Y, Sun, B, Feng, D, Hu, H, Chu, M, Qu, Q, Tarrasch, J.T, Li, S, Kobilka, T.S, Kobilka, B.K, Skiniotis, G.
登録日2017-03-27
公開日2017-05-24
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.
Nature, 546, 2017
5UKL
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BU of 5ukl by Molmil
Human GRK2 in complex with Gbetagamma subunits and CCG222886 (14bd)
分子名称: 2-{5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluorophenyl}-N-[2-(1H-pyrazol-4-yl)ethyl]acetamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cato, M.C, Homan, K.T, Tesmer, J.J.G.
登録日2017-01-23
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.
J. Med. Chem., 60, 2017
5TGM
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BU of 5tgm by Molmil
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Melnikov, S, Mailliot, J, Yusupov, M.
登録日2016-09-28
公開日2017-01-18
最終更新日2022-12-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5T2C
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BU of 5t2c by Molmil
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Zhang, X, Lai, M, Zhou, Z.H.
登録日2016-08-23
公開日2017-01-25
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
5TZS
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BU of 5tzs by Molmil
Architecture of the yeast small subunit processome
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 3' domain-associated, ...
著者Chaker-Margot, M, Barandun, J, Hunziker, M, Klinge, S.
登録日2016-11-22
公開日2016-12-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Architecture of the yeast small subunit processome.
Science, 355, 2017
5VYC
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BU of 5vyc by Molmil
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A.
登録日2017-05-24
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.
Cell Rep, 20, 2017
3J6Y
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BU of 3j6y by Molmil
S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2014-04-16
公開日2014-06-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JAG
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BU of 3jag by Molmil
Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
登録日2015-06-10
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
3JCT
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BU of 3jct by Molmil
Cryo-em structure of eukaryotic pre-60S ribosomal subunits
分子名称: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N.
登録日2016-03-09
公開日2016-06-01
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016

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