PDB: 7770 件ウェブページステータス検索Chemie searchBIRD

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3HB5	Binary and ternary crystal structures of a novel inhibitor of 17 beta-HSD type 1: a lead compound for breast cancer therapy 分子名称: 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide, Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Mazumdar, M, Lin, S.-X. 登録日 2009-05-04 公開日 2009-12-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy. Biochem.J., 424, 2009
3HBW	Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A) 分子名称: Fibroblast growth factor 13 著者 Mohammadi, M. 登録日 2009-05-05 公開日 2009-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels. J.Biol.Chem., 284, 2009
3HCE	Crystal Structure of E185D hPNMT in Complex With Octopamine and AdoHcy 分子名称: 4-(2R-AMINO-1-HYDROXYETHYL)PHENOL, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-05-06 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochem.J., 422, 2009
3GTM	Co-complex of Backtracked RNA polymerase II with TFIIS 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
3GXL	ALK-5 kinase complex with GW857175 分子名称: N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine, TGF-beta receptor type-1 著者 Smith, W, Janson, C. 登録日 2009-04-02 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors Bioorg.Med.Chem.Lett., 19, 2009
3GQY	Activator-Bound Structure of Human Pyruvate Kinase M2 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... 著者 Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2009-03-24 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Activator-Bound Structures of Human Pyruvate Kinase M2 to be published
3GS4	Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid (inhibitor 15) 分子名称: 3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid, Transthyretin 著者 Mohamedmohaideen, N.N, Palaninathan, S.K, Orlandini, E, Sacchettini, J.C. 登録日 2009-03-26 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis. Plos One, 4, 2009
3GSN	Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope 分子名称: Beta-2-microglobulin, CHLORIDE ION, HCMV pp65 fragment 495-503 (NLVPMVATV), ... 著者 Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. 登録日 2009-03-27 公開日 2009-08-04 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
3GU7	Crystal structure of DAPKQ23V-ADP-Mg2+ 分子名称: ADENOSINE-5'-DIPHOSPHATE, Death-associated protein kinase 1, MAGNESIUM ION 著者 McNamara, L.K, Schavocky, J.S, Watterson, D.M, Brunzelle, J.S. 登録日 2009-03-28 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enzyme activity and crystallographic analyses of a glycine-rich loop mutant of DAPK To be Published
3GUS	Crystal strcture of human Pi class glutathione S-transferase GSTP1-1 in complex with 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]hexan-1-ol, GLUTATHIONE, ... 著者 Federici, L, Lo Sterzo, C, Di Matteo, A, Scaloni, F, Federici, G, Caccuri, A.M. 登録日 2009-03-30 公開日 2009-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases Cancer Res., 69, 2009
3GSU	Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5T peptide variant 分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5T (NLVPTVATV), ... 著者 Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. 登録日 2009-03-27 公開日 2009-08-04 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
3GU6	Crystal structure of DAPKQ23V-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Death-associated protein kinase 1 著者 McNamara, L.K, Schavocky, J.S, Watterson, D.M, Brunzelle, J.S. 登録日 2009-03-28 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Enzymatic activity and crystallographic analyses of a glycine-rich loop mutant of DAPK To be Published
3GUB	Crystal structure of DAPKL93G complexed with N6-(2-Phenylethyl)adenosine 分子名称: 9-alpha-L-lyxofuranosyl-N-(2-phenylethyl)-9H-purin-6-amine, Death-associated protein kinase 1, SULFATE ION 著者 McNamara, L.K, Schumacher, A.M, Schavocky, J.S, Watterson, D.M, Brunzelle, J.S. 登録日 2009-03-29 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Crystal structures of the DAPK gatekeeper mutant complexed with N6-modified adenosine analogs. To be Published
3H3C	Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog 分子名称: 4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide, Protein tyrosine kinase 2 beta, SULFATE ION 著者 Han, S, Mistry, A. 登録日 2009-04-16 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity. Bioorg.Med.Chem.Lett., 19, 2009
3GJX	Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R. 登録日 2009-03-09 公開日 2009-05-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP. Science, 2009
3HAH	Crystal structure of human PACSIN1 F-BAR domain (C2 lattice) 分子名称: CALCIUM ION, human PACSIN1 F-BAR 著者 Wang, Q, Navarro, M.V.A.S, Peng, G, Rajashankar, K.R, Sondermann, H. 登録日 2009-05-01 公開日 2009-06-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin. Proc.Natl.Acad.Sci.USA, 106, 2009
3GOF	Calmodulin bound to peptide from macrophage nitric oxide synthase 分子名称: CALCIUM ION, Calmodulin, Nitric oxide synthase, ... 著者 Ng, H.L, Greenstein, A, Marletta, M, Wand, A.J, Alber, T. 登録日 2009-03-19 公開日 2010-03-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural diversity in calmodulin recognition of nitric oxide synthases To be Published
3GPC	Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA 分子名称: Acyl-coenzyme A synthetase ACSM2A, COENZYME A, MAGNESIUM ION 著者 Pilka, E.S, Kochan, G.T, Yue, W.W, Bhatia, C, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2009-03-23 公開日 2009-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A J.Mol.Biol., 388, 2009
3GLS	Crystal Structure of Human SIRT3 分子名称: NAD-dependent deacetylase sirtuin-3, mitochondrial, SULFATE ION, ... 著者 Jin, L, Wei, W, Jiang, Y, Peng, H, Cai, J, Mao, C, Dai, H, Bemis, J.E, Jirousek, M.R, Milne, J.C, Westphal, C.H, Perni, R.B. 登録日 2009-03-12 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284, 2009
3GQR	Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.4 angstrom resolution 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta-A/B, PROTOPORPHYRIN IX CONTAINING FE 著者 Balasubramanian, M, Sathya Moorthy, P, Neelagandan, K, Ponnuswamy, M.N. 登録日 2009-03-24 公開日 2010-03-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.4 angstrom resolution To be Published
3GS7	Human transthyretin (TTR) complexed with (E)-3-(2-methoxybenzylideneaminooxy)propanoic acid (inhibitor 13) 分子名称: 3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid, Transthyretin 著者 Mohamedmohaideen, N.N, Palaninathan, S.K, Orlandini, E, Sacchettini, J.C. 登録日 2009-03-26 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis. Plos One, 4, 2009
3GV4	Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG 分子名称: CALCIUM ION, Histone deacetylase 6, ZINC ION, ... 著者 Dong, A, Ravichandran, M, Loppnau, P, Li, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Dhe-Paganon, S, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) 登録日 2009-03-30 公開日 2009-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG To be Published
3GSO	Crystal structure of the binary complex between HLA-A2 and HCMV NLV peptide 分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503 (NLVPMVATV), HLA class I histocompatibility antigen, ... 著者 Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. 登録日 2009-03-27 公開日 2009-08-04 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
3H44	Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha 分子名称: 1,4-DIETHYLENE DIOXIDE, C-C motif chemokine 3, Insulin-degrading enzyme, ... 著者 Ren, M, Guo, Q, Tang, W.J. 登録日 2009-04-17 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme To be Published
3HAJ	Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice) 分子名称: CALCIUM ION, human PACSIN2 F-BAR 著者 Wang, Q, Navarro, M.V.A.S, Peng, G, Rajashankar, K.R, Sondermann, H. 登録日 2009-05-01 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin. Proc.Natl.Acad.Sci.USA, 106, 2009

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