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3HBW

Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A)

Summary for 3HBW
Entry DOI10.2210/pdb3hbw/pdb
Related1Q1U
DescriptorFibroblast growth factor 13 (2 entities in total)
Functional Keywordsbeta-trefoil fold, alternative splicing, growth factor, polymorphism, hormone
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight43685.74
Authors
Mohammadi, M. (deposition date: 2009-05-05, release date: 2009-05-26, Last modification date: 2023-09-06)
Primary citationGoetz, R.,Dover, K.,Laezza, F.,Shtraizent, N.,Huang, X.,Tchetchik, D.,Eliseenkova, A.V.,Xu, C.F.,Neubert, T.A.,Ornitz, D.M.,Goldfarb, M.,Mohammadi, M.
Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels.
J.Biol.Chem., 284:17883-17896, 2009
Cited by
PubMed: 19406745
DOI: 10.1074/jbc.M109.001842
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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