3GUS
Crystal strcture of human Pi class glutathione S-transferase GSTP1-1 in complex with 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX)
Summary for 3GUS
| Entry DOI | 10.2210/pdb3gus/pdb |
| Related | 3GUR |
| Descriptor | Glutathione S-transferase P, GLUTATHIONE, 6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]hexan-1-ol, ... (6 entities in total) |
| Functional Keywords | gstp1-1 in complex with glutathione and nbdhex, phosphoprotein, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 48188.98 |
| Authors | Federici, L.,Lo Sterzo, C.,Di Matteo, A.,Scaloni, F.,Federici, G.,Caccuri, A.M. (deposition date: 2009-03-30, release date: 2009-10-27, Last modification date: 2023-11-01) |
| Primary citation | Federici, L.,Lo Sterzo, C.,Pezzola, S.,Di Matteo, A.,Scaloni, F.,Federici, G.,Caccuri, A.M. Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases Cancer Res., 69:8025-8034, 2009 Cited by PubMed: 19808963DOI: 10.1158/0008-5472.CAN-09-1314 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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