3GQY

Activator-Bound Structure of Human Pyruvate Kinase M2

Summary for 3GQY

• Entry DOI: 10.2210/pdb3gqy/pdb
• Descriptor: Pyruvate kinase isozymes M1/M2, 1,6-di-O-phosphono-beta-D-fructofuranose, L(+)-TARTARIC ACID, ... (6 entities in total)
• Functional Keywords: activator, acetylation, allosteric enzyme, alternative splicing, glycolysis, kinase, magnesium, metal-binding, phosphoprotein, polymorphism, pyruvate, transferase, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 243370.43

Authors

Hong, B.,Dimov, S.,Tempel, W.,Auld, D.,Thomas, C.,Boxer, M.,Jianq, J.-K.,Skoumbourdis, A.,Min, S.,Southall, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Inglese, J.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-03-24, release date: 2009-04-07, Last modification date: 2023-09-06)

• Primary citation: Hong, B.,Dimov, S.,Tempel, W.,Auld, D.,Thomas, C.,Boxer, M.,Jianq, J.-K.,Skoumbourdis, A.,Min, S.,Southall, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Inglese, J.,Park, H.; Activator-Bound Structures of Human Pyruvate Kinase M2; to be published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)