3GPC
Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA
Replaces: 3EYNSummary for 3GPC
Entry DOI | 10.2210/pdb3gpc/pdb |
Related | 3B7W 3C5E 3DAY 3EQ6 |
Descriptor | Acyl-coenzyme A synthetase ACSM2A, MAGNESIUM ION, COENZYME A, ... (4 entities in total) |
Functional Keywords | middle-chain acyl-coa synthetase, xenobiotic/medium-chain fatty acid-coa ligase, atp-binding, fatty acid metabolism, lipid metabolism, magnesium, metal-binding, mitochondrion, nucleotide-binding polymorphism, transit peptide, ligase, nucleotide-binding |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion matrix : Q08AH3 |
Total number of polymer chains | 2 |
Total formula weight | 128252.80 |
Authors | Pilka, E.S.,Kochan, G.T.,Yue, W.W.,Bhatia, C.,Von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2009-03-23, release date: 2009-04-07, Last modification date: 2023-11-01) |
Primary citation | Kochan, G.,Pilka, E.S.,von Delft, F.,Oppermann, U.,Yue, W.W. Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A J.Mol.Biol., 388:997-1008, 2009 Cited by PubMed: 19345228DOI: 10.1016/j.jmb.2009.03.064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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