3H44
Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha
Summary for 3H44
Entry DOI | 10.2210/pdb3h44/pdb |
Descriptor | Insulin-degrading enzyme, C-C motif chemokine 3, 1,4-DIETHYLENE DIOXIDE, ... (5 entities in total) |
Functional Keywords | ide, mip1alpha, cytoplasm, hydrolase, metal-binding, metalloprotease, polymorphism, protease, zinc, chemotaxis, cytokine, disulfide bond, inflammatory response, secreted, hydrolase-cytokine complex, hydrolase/cytokine |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P14735 Secreted: P10147 |
Total number of polymer chains | 4 |
Total formula weight | 245367.93 |
Authors | Ren, M.,Guo, Q.,Tang, W.J. (deposition date: 2009-04-17, release date: 2010-04-14, Last modification date: 2023-09-06) |
Primary citation | Ren, M.,Guo, Q.,Tang, W.J. Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme To be Published, |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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