PDB: 68 件ウェブページステータス検索Chemie searchBIRD

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2VPF	VASCULAR ENDOTHELIAL GROWTH FACTOR REFINED TO 1.93 ANGSTROMS RESOLUTION 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR 著者 Muller, Y.A, De Vos, A.M. 登録日 1997-07-29 公開日 1998-07-29 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding. Structure, 5, 1997
2VWE	Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment 分子名称: ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B 著者 Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R. 登録日 2008-06-23 公開日 2008-11-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment. J.Mol.Biol., 384, 2008
2XV7	Crystal structure of vascular endothelial growth factor D 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR D, alpha-D-mannopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Leppanen, V.-M, Jeltsch, M, Anisimov, A, Tvorogov, D, Aho, K, Kalkkinen, N, Toivanen, P, Yla-Herttuala, S, Ballmer-Hofer, K, Alitalo, K. 登録日 2010-10-23 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Determinants of Vascular Endothelial Growth Factor-D - Receptor Binding and Specificity. Blood, 117, 2011
5O4E	Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Mlynek, G, Lobner, E, Kubinger, K, Humm, A, Obinger, C, Djinovic-Carugo, K. 登録日 2017-05-29 公開日 2017-08-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex. MAbs, 9, 2017
6BFT	Structure of Bevacizumab Fab mutant in complex with VEGF 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Avastin Heavy Chain Fab fragment mutant, Avastin Light Chain Fab fragment mutant, ... 著者 Christie, M, Christ, D. 登録日 2017-10-27 公開日 2018-10-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Stable human IgG antibody therapeutics with native framework structure To Be Published
4BSK	Crystal structure of VEGF-C in complex with VEGFR-3 domains D1-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, VASCULAR ENDOTHELIAL GROWTH FACTOR C, ... 著者 Leppanen, V.M, Tvorogov, D, Kisko, K, Prota, A.E, Jeltsch, M, Anisimov, A, Markovic-Mueller, S, Stuttfeld, E, Goldie, K.N, Ballmer-Hofer, K, Alitalo, K. 登録日 2013-06-10 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.201 Å) 主引用文献 Structural and Mechanistic Insights Into Vegfr-3 Ligand Binding and Activation Proc.Natl.Acad.Sci.USA, 110, 2013
1FLT	VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR 分子名称: FMS-LIKE TYROSINE KINASE 1, VASCULAR ENDOTHELIAL GROWTH FACTOR 著者 Wiesmann, C, De Vos, A.M. 登録日 1997-11-20 公開日 1999-01-13 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell(Cambridge,Mass.), 91, 1997
1QTY	VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR 分子名称: FMS-LIKE TYROSINE KINASE 1, VASCULAR ENDOTHELIAL GROWTH FACTOR 著者 Wiesmann, C, de Vos, A.M. 登録日 1999-06-29 公開日 2000-01-12 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293, 1999
1RV6	Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLT1 protein, placenta growth factor (PlGF) 著者 Christinger, H.W, Fuh, G, de Vos, A.M, Wiesmann, C. 登録日 2003-12-12 公開日 2004-01-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1. J.Biol.Chem., 279, 2004
3MJK	Structure of a growth factor precursor 分子名称: Platelet-derived growth factor subunit A 著者 Liu, H, He, X. 登録日 2010-04-12 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex. Proc.Natl.Acad.Sci.USA, 107, 2010
2XAC	Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity 分子名称: GLYCEROL, VASCULAR ENDOTHELIAL GROWTH FACTOR B, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 著者 Iyer, S, Darley, P, Acharya, K.R. 登録日 2010-03-30 公開日 2010-05-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural Insights Into the Binding of Vegf-B by Vegfr-1D2: Recognition and Specificity J.Biol.Chem., 285, 2010
5T89	Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ... 著者 Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K. 登録日 2016-09-07 公開日 2017-02-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A. Structure, 25, 2017
3V6B	VEGFR-2/VEGF-E complex structure 分子名称: VEGF-E, Vascular endothelial growth factor receptor 2 著者 Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Kisko, K, Ballmer-Hofer, K. 登録日 2011-12-19 公開日 2012-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.205 Å) 主引用文献 Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119, 2012
3V2A	VEGFR-2/VEGF-A COMPLEX STRUCTURE 分子名称: Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 2 著者 Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Ballmer-Hofer, K. 登録日 2011-12-12 公開日 2012-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.204 Å) 主引用文献 Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119, 2012
4QAF	Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109) 分子名称: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ... 著者 Giese, T, Skerra, A. 登録日 2014-05-04 公開日 2015-05-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold To be Published
3MJG	The structure of a platelet derived growth factor receptor complex 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-type platelet-derived growth factor receptor, ... 著者 Shim, A.H.R, He, X. 登録日 2010-04-12 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex. Proc.Natl.Acad.Sci.USA, 107, 2010
2X1X	CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, ... 著者 Leppanen, V.-M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K. 登録日 2010-01-08 公開日 2010-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2. Proc.Natl.Acad.Sci.USA, 107, 2010
2X1W	Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CESIUM ION, ... 著者 Leppanen, V.M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K. 登録日 2010-01-08 公開日 2010-03-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2. Proc.Natl.Acad.Sci.USA, 107, 2010

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