2XAC

Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity

Summary for 2XAC

Entry DOI	10.2210/pdb2xac/pdb
Related	1FLT 1QSV 1QSZ 1QTY 1RV6 2C7W 2VWE
Descriptor	VASCULAR ENDOTHELIAL GROWTH FACTOR B, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1, GLYCEROL, ... (4 entities in total)
Functional Keywords	transferase-signaling protein complex, angiogenesis, cysteine-knot protein, mitogen, transferase, signaling protein, transferase/signaling protein
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted: P49765 Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948
Total number of polymer chains	4
Total formula weight	44826.06
Authors	Iyer, S.,Darley, P.,Acharya, K.R. (deposition date: 2010-03-30, release date: 2010-05-19, Last modification date: 2023-12-20)
Primary citation	Iyer, S.,Darley, P.,Acharya, K.R. Structural Insights Into the Binding of Vegf-B by Vegfr-1D2: Recognition and Specificity J.Biol.Chem., 285:23779-, 2010 Cited by PubMed: 20501651 DOI: 10.1074/JBC.M110.130658 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation