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2XAC

Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity

Functional Information from GO Data
ChainGOidnamespacecontents
A0008083molecular_functiongrowth factor activity
A0016020cellular_componentmembrane
B0008083molecular_functiongrowth factor activity
B0016020cellular_componentmembrane
C0005021molecular_functionvascular endothelial growth factor receptor activity
C0005524molecular_functionATP binding
C0005886cellular_componentplasma membrane
C0006468biological_processprotein phosphorylation
C0048010biological_processvascular endothelial growth factor receptor signaling pathway
X0005021molecular_functionvascular endothelial growth factor receptor activity
X0005524molecular_functionATP binding
X0005886cellular_componentplasma membrane
X0006468biological_processprotein phosphorylation
X0048010biological_processvascular endothelial growth factor receptor signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL B 1109
ChainResidue
AGLN73
AHIS74
ASER99
AHOH2009
BGLN73
BHIS74
BSER99

Functional Information from PROSITE/UniProt
site_idPS00249
Number of Residues13
DetailsPDGF_1 Platelet-derived growth factor (PDGF) family signature. PSCVtvqRCGGCC
ChainResidueDetails
APRO49-CYS61

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues126
DetailsDomain: {"description":"Ig-like C2-type 2"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

239492

PDB entries from 2025-07-30

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