4BSK

Crystal structure of VEGF-C in complex with VEGFR-3 domains D1-2

Summary for 4BSK

• Entry DOI: 10.2210/pdb4bsk/pdb
• Related: 4BSJ
• Descriptor: VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3, VASCULAR ENDOTHELIAL GROWTH FACTOR C, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: transferase-hormone complex, transferase, lymphangiogenesis, angiogenesis, ig domain, glycoprotein, receptor tyrosine kinase, dimerization, transferase/hormone
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 38760.34

Authors

Leppanen, V.M.,Tvorogov, D.,Kisko, K.,Prota, A.E.,Jeltsch, M.,Anisimov, A.,Markovic-Mueller, S.,Stuttfeld, E.,Goldie, K.N.,Ballmer-Hofer, K.,Alitalo, K. (deposition date: 2013-06-10, release date: 2013-07-31, Last modification date: 2023-12-20)

• Primary citation: Leppanen, V.-M.,Tvorogov, D.,Kisko, K.,Prota, A.E.,Jeltsch, M.,Anisimov, A.,Markovic-Mueller, S.,Stuttfeld, E.,Goldie, K.N.,Ballmer-Hofer, K.,Alitalo, K.; Structural and Mechanistic Insights Into Vegfr-3 Ligand Binding and Activation; Proc.Natl.Acad.Sci.USA, 110:12960-, 2013; PubMed: 23878260; DOI: 10.1073/PNAS.1301415110

Experimental method

X-RAY DIFFRACTION (4.201 Å)